Biosensing of Molecular Behavior of Liposome and Target Protein, and their Interaction by Dielectric Dispersion Analysis for 100-1000 MHz Range

AbstractWe have examined biochemical interaction between liposome and target proteins by Dielectric Dispersion Analysis (DDA), especially for frequency range of 100-1000MHz to consider molecular dynamics of the coexistence of the liposome membrane and target protein. Finally, we newly observed several new dielectric relaxations by the interaction in the low frequency range, thereafter we newly found and considered that some interaction manners between the each protein against liposome would exist and be different at least qualitatively for the two proteins because the manner of change in relaxation was different between each other