AbstractIn mammals, most new mutations occur in males. But a study of the evolution of a human X to Y chromosomal translocation has revealed a sex bias much lower than previous estimates. Patterns of substitution suggest that differential methylation between male and female germ lines is a key determinant of the mutation rate
The ability of a population to adapt to changing environments depends critically on the amount and k...
Sex chromosomes are advantageous to mammals, allowing them to adopt a genetic rather than environmen...
The canonical model of sex-chromosome evolution predicts that sex-antagonistic (SA) genes play an in...
Rates of mutation and substitution in mammals are generally greater in the germ lines of males. This...
Mutation generates a steady supply of genetic variation that, while occasionally useful for adaptati...
Germ line mutation determines rates of molecular evolution, genetic diversity and fitness load. In ...
International audienceWe simulated a meta-population with random dispersal among demes but local mat...
International audienceWe simulated a meta-population with random dispersal among demes but local mat...
Regional biases in substitution pattern are likely to be responsible for the large-scale variation i...
SummaryIn many animal species, males suffer more from age-related disease than females. Is there a c...
In many species, spermatogenesis involves more cell divisions than oogenesis, and the male germline...
ABSTRACT Because the two sexes share a common gene pool while performing many different biological f...
Due to its hemizygous inheritance and role in sex determination, the X-chromosome is expected to pla...
Recombination arrest between X and Y chromosomes, driven by sexually antagonistic genes, is expected...
Background: Variation in the non-coding regions of Y-chromosomes have been shown to influence gene r...
The ability of a population to adapt to changing environments depends critically on the amount and k...
Sex chromosomes are advantageous to mammals, allowing them to adopt a genetic rather than environmen...
The canonical model of sex-chromosome evolution predicts that sex-antagonistic (SA) genes play an in...
Rates of mutation and substitution in mammals are generally greater in the germ lines of males. This...
Mutation generates a steady supply of genetic variation that, while occasionally useful for adaptati...
Germ line mutation determines rates of molecular evolution, genetic diversity and fitness load. In ...
International audienceWe simulated a meta-population with random dispersal among demes but local mat...
International audienceWe simulated a meta-population with random dispersal among demes but local mat...
Regional biases in substitution pattern are likely to be responsible for the large-scale variation i...
SummaryIn many animal species, males suffer more from age-related disease than females. Is there a c...
In many species, spermatogenesis involves more cell divisions than oogenesis, and the male germline...
ABSTRACT Because the two sexes share a common gene pool while performing many different biological f...
Due to its hemizygous inheritance and role in sex determination, the X-chromosome is expected to pla...
Recombination arrest between X and Y chromosomes, driven by sexually antagonistic genes, is expected...
Background: Variation in the non-coding regions of Y-chromosomes have been shown to influence gene r...
The ability of a population to adapt to changing environments depends critically on the amount and k...
Sex chromosomes are advantageous to mammals, allowing them to adopt a genetic rather than environmen...
The canonical model of sex-chromosome evolution predicts that sex-antagonistic (SA) genes play an in...
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