0308: Obstructive sleep apnea and acute coronary syndromes: comparison of clinical and angiographic characteristics

IntroductionObstructive sleep apnea hypopnea syndrome (OSAHS) is associated with a range of cardiovascular diseases and increase cardiovascular mortality.AimThe aim of this study was to compare the clinical and angiographic characteristics of patients admitted for acute coronary syndromes (ACS) with and without OSAHS.MethodsWe examined the apnea hypopnea index (AHI) using polygraphy (PG) in 60 consecutive patients with ACS who underwent coronary angiography. OSAHS was defined by AHI≥5 events per hour. The Friesinger score was calculated for each patient from the coronary angiography.ResultsThe average age of patients was 59.73 years±10.1 years. The sex ratio was 1.5. The distribution of risk factors was as follows: hypertension in 61.7% of cases, diabetes in 58.4% of cases, smoking in 51.7% of cases and dyslipidemia in 40% of cases. The mean body mass index (BMI) was 27.98kg/m2.The average of ejection fraction was 54%±15.87.61,7% of patients had an AHI≥5. There were no differences between patients having OSAHS and those without OSAHS regarding clinical and angiographic characteristics. The table summarizes these results.Abstratct 0308 – Table: Comparison of patients with and without OSAHSOSAHS n=37No OSAHS n=23PAge61,22±9,357,35±11,20,15Male35%25%0,51BMI27,94±3,9328,05±4,040,92Smoking28,3%23,3%0,26Hypertension40%21,7%0,51Ddiabetes31,7%26,7%0,16BMI27,94±3,9328,05±4,040,923 vessel disease (%)21,7%16,70,51Friesinger score8,6±4,88,65±5,440,97ConclusionIn conclusion, we noted a high incidence of OSAHS in ACS in our population. There is no difference between ACS patients with and without OSAHS. This latter doesn’t seem related to the severity of the coronary disease. Further studies are needed to evaluate the impact of the presence of OSAHS on short and long term prognosis