Similarities between basal cell carcinoma (BCC) tumor cells and hair follicle keratinocytes had previously suggested that BCC originates within the hair follicle bulge stem cell niche. However, in the current Nature Cell Biology, Youssef et al. (2010) show that BCC instead originates in the interfollicular epidermis
In this issue of Cell Stem Cell, Brownell et al. (2011) identify stem cells in the hair follicle bul...
SummaryIn adult skin, stem cells in the hair follicle bulge cyclically regenerate the follicle, wher...
Skin cancers are very common in humans. The two most frequent epithelial skin cancers are the basal ...
SummaryBasal cell carcinomas (BCCs) are hedgehog-driven tumors that resemble follicular and interfol...
For most types of cancers, the cell at the origin of tumour initiation is still unknown. Here, we us...
For most types of cancers, the cell at the origin of tumour initiation is still unknown. Here, we us...
Wong and Reiter have explored the possibility that hair follicle stem cells can give rise to basal c...
Similarities between basal cell carcinoma (BCC) tumor cells and hair follicle keratinocytes had prev...
The cell of origin for basal cell carcinoma (BCC) remains controversial. In this issue of Cancer Cel...
SummaryBasal cell carcinoma (BCC) is characterized by frequent loss of PTCH1, leading to constitutiv...
Putative epithelial stem cells were identified in the hair follicle bulge as quiescent “label retain...
Inconsistent with the view that hair follicle stem cells reside in the matrix area of the hair bulb,...
Putative epithelial stem cells were identified in the hair follicle bulge as quiescent ‘‘label retai...
stem cells have the unique capacity to self-newal and to differentiate into the cell lineages that c...
SummaryThe regeneration of the skin and its appendages is thought to occur by the regulated activati...
In this issue of Cell Stem Cell, Brownell et al. (2011) identify stem cells in the hair follicle bul...
SummaryIn adult skin, stem cells in the hair follicle bulge cyclically regenerate the follicle, wher...
Skin cancers are very common in humans. The two most frequent epithelial skin cancers are the basal ...
SummaryBasal cell carcinomas (BCCs) are hedgehog-driven tumors that resemble follicular and interfol...
For most types of cancers, the cell at the origin of tumour initiation is still unknown. Here, we us...
For most types of cancers, the cell at the origin of tumour initiation is still unknown. Here, we us...
Wong and Reiter have explored the possibility that hair follicle stem cells can give rise to basal c...
Similarities between basal cell carcinoma (BCC) tumor cells and hair follicle keratinocytes had prev...
The cell of origin for basal cell carcinoma (BCC) remains controversial. In this issue of Cancer Cel...
SummaryBasal cell carcinoma (BCC) is characterized by frequent loss of PTCH1, leading to constitutiv...
Putative epithelial stem cells were identified in the hair follicle bulge as quiescent “label retain...
Inconsistent with the view that hair follicle stem cells reside in the matrix area of the hair bulb,...
Putative epithelial stem cells were identified in the hair follicle bulge as quiescent ‘‘label retai...
stem cells have the unique capacity to self-newal and to differentiate into the cell lineages that c...
SummaryThe regeneration of the skin and its appendages is thought to occur by the regulated activati...
In this issue of Cell Stem Cell, Brownell et al. (2011) identify stem cells in the hair follicle bul...
SummaryIn adult skin, stem cells in the hair follicle bulge cyclically regenerate the follicle, wher...
Skin cancers are very common in humans. The two most frequent epithelial skin cancers are the basal ...