Drug eluted balloon has the potential to treat in-stent restenosis and small vessels disease

BackgroundIn-stent restenosis still a major problem after percutanous coronary intervention. One-quarter of DESs can result in restenosis, paclitaxel-coated coronary balloons showed an advantage in patients with in-stent restenosis in different clinical studies, small vessels disease is a challenge in coronary interventionMethodsSingle center study in our cath lab between Jan 2010–Oct 2011, a total of 36 patients, with either in-stent restenosis more than 50%, or small vessel disease, under went balloon angioplasty using a Dior Eurocor, Drug Eluted Balloon to treat those lesions. And patients were prepared in the same way of regular PCI, given heparin and clopidogrel loading and maintenance dose accordingly. We are planning to f/u the patients clinically for 6 months to 2 years.ResultsTotal of 36 patients, 10 (28%) patients had in-stent restenosis treated by DEB. 26 (72%) patients had a small vessels disease, diameter