AbstractWe relate the ultrastructure of the giant bipolar synapse in goldfish retina to the jump in capacitance that accompanies depolarization-evoked exocytosis. Mean vesicle diameter is 29 ± 4 nm, giving 26.4 aF/vesicle, so the maximum evoked capacitance (150 fF within 200 ms) represents fusion of about 5700 vesicles. Two terminals contained, respectively, 45 and 65 ribbon-type synaptic outputs, and a fully loaded ribbon tethers about 110 vesicles. Thus, the tethered pool, about 6000 vesicles, corresponds to the rapidly released pool. Further, the difference between small and large terminals in number of tethered vesicles matches their difference in capacitance jump. This suggests, within a “fire and reload” model of exocytosis, that the ...
Ribbon synapses of the vertebrate retina are specialized synapses that release neurotransmitter by s...
AbstractThe rate of release from nerve terminals depends on both the number of release sites and the...
AbstractEndocytosis and exocytosis were investigated in the synaptic terminal of retinal bipolar cel...
AbstractWe relate the ultrastructure of the giant bipolar synapse in goldfish retina to the jump in ...
Ribbon synapses are found in sensory systems and are characterized by ‘ribbon-like’ organelles that ...
Background: Most synapses release neurotransmitter as transient pulses, but ribbon synapses of senso...
Ribbon synapses of sensory neurons are able to sustain high rates of exocytosis in response to maint...
Background: Most synapses release neurotransmitter as transient pulses, but ribbon synapses of senso...
Most synapses release neurotransmitter as transient pulses, but ribbon synapses of sensory neurons s...
AbstractUsing high resolution capacitance measurements, we have characterized an ultrafast component...
AbstractExocytosis-mediated glutamate release from ribbon-type synaptic terminals of retinal bipolar...
The distribution of exocytic sites and ion channels in the synaptic terminal of retinal bipolar cell...
Following synaptic vesicle exocytosis, neurons retrieve the fused membrane by a process of endocytos...
To better understand synaptic signaling at the mammalian rod bipolar cell terminal and pave the way ...
The mechanism of bulk membrane uptake at the synapse remains poorly defined, although exocytosis of ...
Ribbon synapses of the vertebrate retina are specialized synapses that release neurotransmitter by s...
AbstractThe rate of release from nerve terminals depends on both the number of release sites and the...
AbstractEndocytosis and exocytosis were investigated in the synaptic terminal of retinal bipolar cel...
AbstractWe relate the ultrastructure of the giant bipolar synapse in goldfish retina to the jump in ...
Ribbon synapses are found in sensory systems and are characterized by ‘ribbon-like’ organelles that ...
Background: Most synapses release neurotransmitter as transient pulses, but ribbon synapses of senso...
Ribbon synapses of sensory neurons are able to sustain high rates of exocytosis in response to maint...
Background: Most synapses release neurotransmitter as transient pulses, but ribbon synapses of senso...
Most synapses release neurotransmitter as transient pulses, but ribbon synapses of sensory neurons s...
AbstractUsing high resolution capacitance measurements, we have characterized an ultrafast component...
AbstractExocytosis-mediated glutamate release from ribbon-type synaptic terminals of retinal bipolar...
The distribution of exocytic sites and ion channels in the synaptic terminal of retinal bipolar cell...
Following synaptic vesicle exocytosis, neurons retrieve the fused membrane by a process of endocytos...
To better understand synaptic signaling at the mammalian rod bipolar cell terminal and pave the way ...
The mechanism of bulk membrane uptake at the synapse remains poorly defined, although exocytosis of ...
Ribbon synapses of the vertebrate retina are specialized synapses that release neurotransmitter by s...
AbstractThe rate of release from nerve terminals depends on both the number of release sites and the...
AbstractEndocytosis and exocytosis were investigated in the synaptic terminal of retinal bipolar cel...