Titin (also known as connectin) is a muscle-specific giant protein found inside the sarcomere, spanning from the Z-line to the M-line. The I-band segment of titin is considered to function as a molecular spring that develops tension when sarcomeres are stretched (passive tension). Recent studies on skeletal muscle indicate that it is not the entire I-band segment of titin that behaves as a spring; some sections are inelastic and do not take part in the development of passive tension. To better understand the mechanism of passive tension development in the heart, where passive tension plays an essential role in the pumping function, we investigated titin's elastic segment in cardiac myocytes using structural and mechanical techniques. Single...
Titin is a giant muscle protein with a molecular weight in the megaDalton range and a contour length...
Titin (also known as connectin) is an intrasarcomeric muscle protein that functions as a molecular s...
Titin is responsible for the passive elasticity of the muscle sarcomere. The mechanical properties o...
Titin (also known as connectin) is a giant filamentous protein whose elastic properties greatly cont...
Titin, the giant protein of striated muscle, provides a continuous link between the Z-disk and the M...
International audienceTitin is a giant filamentous polypeptide of multi-domain construction spanning...
Vertebrate striated muscle behaves elastically when stretched and this1Institute of Physiology II pr...
Titin (also known as connectin) is a giant filamentous protein whose elastic properties greatly cont...
The high stiffness of relaxed cardiac myofibrils is explainable mainly by the expression of a short-...
The giant muscle protein titin has become a focus of research interests in the field of muscle mecha...
Linke WA, Ivemeyer M, Labeit S, Hinssen H, Ruegg JC, Gautel M. Actin-titin interaction in cardiac my...
Titin is responsible for the passive elasticity of the muscle sarcomere. The mechanical properties o...
AbstractTitin (also known as connectin) is an intrasarcomeric muscle protein that functions as a mol...
The passive tension-sarcomere length relation of rat cardiac muscle was investigated by studying pas...
Titins are megadalton-sized filamentous polypeptides of vertebrate striated muscle. The I-band regio...
Titin is a giant muscle protein with a molecular weight in the megaDalton range and a contour length...
Titin (also known as connectin) is an intrasarcomeric muscle protein that functions as a molecular s...
Titin is responsible for the passive elasticity of the muscle sarcomere. The mechanical properties o...
Titin (also known as connectin) is a giant filamentous protein whose elastic properties greatly cont...
Titin, the giant protein of striated muscle, provides a continuous link between the Z-disk and the M...
International audienceTitin is a giant filamentous polypeptide of multi-domain construction spanning...
Vertebrate striated muscle behaves elastically when stretched and this1Institute of Physiology II pr...
Titin (also known as connectin) is a giant filamentous protein whose elastic properties greatly cont...
The high stiffness of relaxed cardiac myofibrils is explainable mainly by the expression of a short-...
The giant muscle protein titin has become a focus of research interests in the field of muscle mecha...
Linke WA, Ivemeyer M, Labeit S, Hinssen H, Ruegg JC, Gautel M. Actin-titin interaction in cardiac my...
Titin is responsible for the passive elasticity of the muscle sarcomere. The mechanical properties o...
AbstractTitin (also known as connectin) is an intrasarcomeric muscle protein that functions as a mol...
The passive tension-sarcomere length relation of rat cardiac muscle was investigated by studying pas...
Titins are megadalton-sized filamentous polypeptides of vertebrate striated muscle. The I-band regio...
Titin is a giant muscle protein with a molecular weight in the megaDalton range and a contour length...
Titin (also known as connectin) is an intrasarcomeric muscle protein that functions as a molecular s...
Titin is responsible for the passive elasticity of the muscle sarcomere. The mechanical properties o...