Leptin mimics many of the antidiabetic actions of insulin in insulin-deficient diabetes, but the mechanism is controversial. Fujikawa et al. (2013) reveal that leptin receptors in γ-aminobutyric acid (GABA)-ergic and pro-opiomelanocortin (POMC) neurons in the central nervous system are sufficient to mediate the lifesaving and antidiabetic actions of leptin in insulin-deficient mice
Obesity and diabetes mellitus are great public health concerns throughout the world because of their...
SummaryLeptin plays a pivotal role in regulation of energy balance. Via unknown central pathways, le...
SummaryThe hormone leptin plays a crucial role in maintenance of body weight and glucose homeostasis...
Leptin mimics many of the antidiabetic actions of insulin in insulin-deficient diabetes, but the mec...
The dogma that life without insulin is incompatible has recently been challenged by results showing ...
SummaryThe dogma that life without insulin is incompatible has recently been challenged by results s...
The dogma that life without insulin is incompatible has recently been challenged by results showing ...
SummaryLeptin has beneficial effects on glucose metabolism via actions in the hypothalamus, but the ...
Leptin has beneficial effects on glucose metabolism via actions in the hypothalamus, but the roles o...
Type 1 diabetes is a life-long disease, with devastating consequences and no cure. While the hormone...
The hormone leptin reduces food intake and increases energy expenditure; leptin deficient rodents an...
The fat derived hormone leptin plays a crucial role in the normal maintenance of body weight and ene...
It has long been thought that the only hormone capable of reversing the catabolic consequences of di...
Leptin action on its receptor (LEPR) stimulates energy expenditure and reduces food intake, thereby ...
SummaryCirculating leptin and insulin convey information regarding energy stores to the central nerv...
Obesity and diabetes mellitus are great public health concerns throughout the world because of their...
SummaryLeptin plays a pivotal role in regulation of energy balance. Via unknown central pathways, le...
SummaryThe hormone leptin plays a crucial role in maintenance of body weight and glucose homeostasis...
Leptin mimics many of the antidiabetic actions of insulin in insulin-deficient diabetes, but the mec...
The dogma that life without insulin is incompatible has recently been challenged by results showing ...
SummaryThe dogma that life without insulin is incompatible has recently been challenged by results s...
The dogma that life without insulin is incompatible has recently been challenged by results showing ...
SummaryLeptin has beneficial effects on glucose metabolism via actions in the hypothalamus, but the ...
Leptin has beneficial effects on glucose metabolism via actions in the hypothalamus, but the roles o...
Type 1 diabetes is a life-long disease, with devastating consequences and no cure. While the hormone...
The hormone leptin reduces food intake and increases energy expenditure; leptin deficient rodents an...
The fat derived hormone leptin plays a crucial role in the normal maintenance of body weight and ene...
It has long been thought that the only hormone capable of reversing the catabolic consequences of di...
Leptin action on its receptor (LEPR) stimulates energy expenditure and reduces food intake, thereby ...
SummaryCirculating leptin and insulin convey information regarding energy stores to the central nerv...
Obesity and diabetes mellitus are great public health concerns throughout the world because of their...
SummaryLeptin plays a pivotal role in regulation of energy balance. Via unknown central pathways, le...
SummaryThe hormone leptin plays a crucial role in maintenance of body weight and glucose homeostasis...