A clean and highly efficient synthesis of 4,4′-(arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ols) using Ce(SO4)2.4H2O as heterogeneous catalyst

AbstractThe synthesis of 4,4′-(arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ol) was performed effectively by the reaction of aryl aldehydes and 1-phenyl-3-methyl-5-pyrazolone in the presence of a catalytic amount of Ce(SO4)2.4H2O as reusable and environmentally friendly catalyst in water/ethanol solution within 5–25min in 80–98% yields. All of the obtained compounds were characterized by FT IR, 1H and 13C NMR. The method has the advantages of high yields, short reaction time, simple work-up and reusability of catalyst