SummaryObjectiveTo characterize the post-expansion cartilage-forming capacity of chondrocytes harvested from detached fragments of osteochondral lesions (OCLs) of ankle joints (Damaged Ankle Cartilage Fragments, DACF), with normal ankle cartilage (NAC) as control.DesignDACF were obtained from six patients (mean age: 35years) with symptomatic OCLs of the talus, while NAC were from 10 autopsies (mean age: 55 years). Isolated chondrocytes were expanded for two passages and then cultured in pellets for 14 days or onto HYAFF®-11 meshes (FAB, Italy) for up to 28 days. Resulting tissues were assessed histologically, biochemically [glycosaminoglycan (GAG), DNA and type II collagen (CII)] and biomechanically.ResultsAs compared to NAC, DACF contained...
BACKGROUND: Large talar cartilage defects can be treated with either autologous chondrocyte implanta...
Regenerative medicine techniques are currently being investigated to replace damaged cartilage. Crit...
[[abstract]]Repair of articular cartilage damage has been a great clinical issue due to the difficul...
SummaryObjectiveTo characterize the post-expansion cartilage-forming capacity of chondrocytes harves...
SummaryObjectiveAutologous chondrocyte implantation (ACI) has been successfully used for the treatme...
SummaryObjectiveAs compared to knee chondrocytes (KC), talar chondrocytes (TC) have superior synthet...
OBJECTIVE: This study aimed to investigate the regenerative capacity of chondrocytes derived from de...
Given articular cartilage has a limited repair potential, untreated osteochondral lesions of the ank...
Loose fragments in osteochondritis dissecans (OCD) of the knee require internal fixation. On the oth...
Objective: This study aimed to investigate the regenerative capacity of chondrocytes derived from de...
OBJECTIVE: Interactions between chondrocytes and their native pericellular matrix provide optimal ci...
<div><p>Lesions of hyaline cartilage do not heal spontaneously, and represent a therapeutic challeng...
Purpose: Minced chondral fragments are becoming popular as a source of cells for cartilage repair, a...
Category: Ankle, Arthroscopy, Sports Introduction/Purpose: A promising new technique in the treatmen...
Injuries to human native cartilage tissue are particularly troublesome because cartilage has little ...
BACKGROUND: Large talar cartilage defects can be treated with either autologous chondrocyte implanta...
Regenerative medicine techniques are currently being investigated to replace damaged cartilage. Crit...
[[abstract]]Repair of articular cartilage damage has been a great clinical issue due to the difficul...
SummaryObjectiveTo characterize the post-expansion cartilage-forming capacity of chondrocytes harves...
SummaryObjectiveAutologous chondrocyte implantation (ACI) has been successfully used for the treatme...
SummaryObjectiveAs compared to knee chondrocytes (KC), talar chondrocytes (TC) have superior synthet...
OBJECTIVE: This study aimed to investigate the regenerative capacity of chondrocytes derived from de...
Given articular cartilage has a limited repair potential, untreated osteochondral lesions of the ank...
Loose fragments in osteochondritis dissecans (OCD) of the knee require internal fixation. On the oth...
Objective: This study aimed to investigate the regenerative capacity of chondrocytes derived from de...
OBJECTIVE: Interactions between chondrocytes and their native pericellular matrix provide optimal ci...
<div><p>Lesions of hyaline cartilage do not heal spontaneously, and represent a therapeutic challeng...
Purpose: Minced chondral fragments are becoming popular as a source of cells for cartilage repair, a...
Category: Ankle, Arthroscopy, Sports Introduction/Purpose: A promising new technique in the treatmen...
Injuries to human native cartilage tissue are particularly troublesome because cartilage has little ...
BACKGROUND: Large talar cartilage defects can be treated with either autologous chondrocyte implanta...
Regenerative medicine techniques are currently being investigated to replace damaged cartilage. Crit...
[[abstract]]Repair of articular cartilage damage has been a great clinical issue due to the difficul...