0135: Cardiogenic shock in elderly patients with acute myocardial infarction. The FAST-MI programme

RationaleThough cardiogenic shock (CS) after AMI is more common in the elderly, information on its prevalence, determinants and prognostic factors in the aged is scarce.MethodsWe analysed incidence and 1-year mortality of CS in 4 nationwide French surveys carried out 5 years apart from 1995 to 2010, including consecutive STEMI and NSTEMI patients over one-month periods.ResultsAmong the 10,610 patients, 3,389 were aged≥75 years, of whom 9.9% developed CS.Incidence of CS decreased from 11.6% in 1995 to 6.7% in 2010, P=0.02. Use of PCI≤3 days from admission increased for both patients with and without CS (11% to 48% and 5% to 55%, respectively), as did statin use (1% to 70% and 4% to 82%, respectively). Occurrence of atrial and ventricular fibrillation decreased in patients without CS (22% to 9%, and 3.6% to 1.5%, respectively, P<0.001), but not in those with CS (19% to 20%, and 10% to 8%, respectively).Conversely, AV block decreased in patients with (30% to 11%) or without CS (9% to 3%).One-year mortality was 77% in CS patients, versus 22% in patients without CS. From 1995 to 2010, mortality decreased from 87% to 59% in CS patients and from 30% to 17% in patients without CS (P