AbstractRecent work in Xenopus embryos reveals an unexpected developmental role for the tumor suppressor gene p53. This finding may have implications for the evolution of p53, its interaction with Smads in TGF-β dependent mesoderm specification, and the cooperation among p53 family members
SummaryDuring gastrulation of the amphibian embryo, specification of the three germ layers, endo-, e...
AbstractAn increasing body of evidence indicates that p53, the product of a tumour suppressor gene, ...
AbstractBackground: The invertebrate and vertebrate Smad proteins have recently been identified as i...
The p53 tumor suppressor belongs to a family of proteins that sense multiple cellular inputs to regu...
AbstractThe p53 tumor suppressor belongs to a family of proteins that sense multiple cellular inputs...
AbstractBackground: The tumor suppressor p53 plays a key role in regulating the cell cycle and apopt...
textp53 family members play an essential role in tumor suppression and development. In this report,...
The p53 tumor suppressor is the focus of intense investigation. It is considered a latent transcript...
Among its multiple functions, p53 is a critical regulator of TGF-β responses. Sasai et al. (2008) no...
Abstractp63, a homolog of the tumor suppressor p53, is critical for the development and maintenance ...
Wild-type p53 and TGF-ß are key tumour suppressors which regulate an array of cellular responses. TG...
p53 is a protein with many talents. One of the most fundamental is the ability to act as essential g...
A fundamental function of the tumor suppressors p53 and TGFβ is protection of cells against cellular...
The Mdn2 gene is the best known cellular regulator of p53 tumor suppressor activity. We report here ...
EMSY interacts directly with BRCA2 and links the BRCA2 pathway to sporadic breast and ovarian cancer...
SummaryDuring gastrulation of the amphibian embryo, specification of the three germ layers, endo-, e...
AbstractAn increasing body of evidence indicates that p53, the product of a tumour suppressor gene, ...
AbstractBackground: The invertebrate and vertebrate Smad proteins have recently been identified as i...
The p53 tumor suppressor belongs to a family of proteins that sense multiple cellular inputs to regu...
AbstractThe p53 tumor suppressor belongs to a family of proteins that sense multiple cellular inputs...
AbstractBackground: The tumor suppressor p53 plays a key role in regulating the cell cycle and apopt...
textp53 family members play an essential role in tumor suppression and development. In this report,...
The p53 tumor suppressor is the focus of intense investigation. It is considered a latent transcript...
Among its multiple functions, p53 is a critical regulator of TGF-β responses. Sasai et al. (2008) no...
Abstractp63, a homolog of the tumor suppressor p53, is critical for the development and maintenance ...
Wild-type p53 and TGF-ß are key tumour suppressors which regulate an array of cellular responses. TG...
p53 is a protein with many talents. One of the most fundamental is the ability to act as essential g...
A fundamental function of the tumor suppressors p53 and TGFβ is protection of cells against cellular...
The Mdn2 gene is the best known cellular regulator of p53 tumor suppressor activity. We report here ...
EMSY interacts directly with BRCA2 and links the BRCA2 pathway to sporadic breast and ovarian cancer...
SummaryDuring gastrulation of the amphibian embryo, specification of the three germ layers, endo-, e...
AbstractAn increasing body of evidence indicates that p53, the product of a tumour suppressor gene, ...
AbstractBackground: The invertebrate and vertebrate Smad proteins have recently been identified as i...
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