The ability of the gut epithelium to defend against pathogens while tolerating harmless commensal organisms remains an important puzzle. In this issue of Cell Host & Microbe, Lee et al. (2015) reveal how pathogen-secreted uracil acts at two steps to induce ROS via the Hedgehog pathway
The human gastrointestinal tract is colonized by at least 400 different microbial species, known as ...
The Hedgehog (Hh) cell–cell signaling pathway is conserved in animals and has critical roles in embr...
SummaryThe molecule Hedgehog is well known as an organizer of tissue morphogenesis. A recent report ...
SummaryGenetic studies in Drosophila have demonstrated that generation of microbicidal reactive oxyg...
Genetic studies in Drosophila have demonstrated that generation of microbicidal reactive oxygen spec...
Genetic studies in Drosophila have demonstrated that generation of microbicidal reactive oxygen spec...
The metazoan gut harbors microbial communities on its mucosal surfaces, yet the mechanisms by which ...
All metazoan guts are subjected to immunologically unique conditions in which an efficient antimicro...
The hedgehog (Hh) signaling pathway plays several diverse regulatory and patterning roles during org...
The hedgehog signalling pathway is critical to normal mammalian gastrointestinal development. Throug...
The hedgehog pathway, which plays a significant role in embryonic development and stem cell regulati...
textabstractEver since its initial discovery in Drosophila, hedgehog signaling has been linked to fo...
The Hedgehog (Hh) signaling pathway plays an essential role in the growth, development, and homeosta...
Since its initial discovery in Drosophila, Hedgehog (HH) signaling has long been associated with for...
Upon intestinal epithelial damage a complex wound healing response is initiated to restore epithelia...
The human gastrointestinal tract is colonized by at least 400 different microbial species, known as ...
The Hedgehog (Hh) cell–cell signaling pathway is conserved in animals and has critical roles in embr...
SummaryThe molecule Hedgehog is well known as an organizer of tissue morphogenesis. A recent report ...
SummaryGenetic studies in Drosophila have demonstrated that generation of microbicidal reactive oxyg...
Genetic studies in Drosophila have demonstrated that generation of microbicidal reactive oxygen spec...
Genetic studies in Drosophila have demonstrated that generation of microbicidal reactive oxygen spec...
The metazoan gut harbors microbial communities on its mucosal surfaces, yet the mechanisms by which ...
All metazoan guts are subjected to immunologically unique conditions in which an efficient antimicro...
The hedgehog (Hh) signaling pathway plays several diverse regulatory and patterning roles during org...
The hedgehog signalling pathway is critical to normal mammalian gastrointestinal development. Throug...
The hedgehog pathway, which plays a significant role in embryonic development and stem cell regulati...
textabstractEver since its initial discovery in Drosophila, hedgehog signaling has been linked to fo...
The Hedgehog (Hh) signaling pathway plays an essential role in the growth, development, and homeosta...
Since its initial discovery in Drosophila, Hedgehog (HH) signaling has long been associated with for...
Upon intestinal epithelial damage a complex wound healing response is initiated to restore epithelia...
The human gastrointestinal tract is colonized by at least 400 different microbial species, known as ...
The Hedgehog (Hh) cell–cell signaling pathway is conserved in animals and has critical roles in embr...
SummaryThe molecule Hedgehog is well known as an organizer of tissue morphogenesis. A recent report ...