SummaryObjectiveTo examine the effect of oestrogen depletion produced by surgical ovariectomy on the structural and biomechanical properties of ovine femoro-tibial articular cartilage (AC), and the production of inducible nitric oxide synthase (iNOS) and nitrotyrosine by these tissues.MethodsSix aged ewes were surgically ovariectomised (OVX), while six were used as unoperated controls. Dynamic biomechanical indentation testing of tibial plateau AC was performed at 26 weeks post-op. Histological sections of medial tibial plateau and lateral tibial plateau (LTP), medial and lateral femoral condyles (MFC, LFC) and patellar AC were examined for histopathology, toluidine blue staining intensity, and patterns of collagen birefringence intensity. ...
AbstractObjectivesOur primary objective was to explore the full potential of the ovine medial menisc...
SummaryAimTo examine the effect of glyceryl trinitrate (GTN), a nitric oxide (NO) donor compound, on...
AbstractObjective The relationship between the topographical variations in the structural, biochemic...
SummaryObjectiveTo examine the effect of oestrogen depletion produced by surgical ovariectomy on the...
SummaryCartilage is a sex-hormone-sensitive tissue but the role of estrogen in the pathogenesis of o...
SummaryCartilage is a sex-hormone-sensitive tissue but the role of estrogen in the pathogenesis of o...
Sheep are a practical model for postmenopausal pathologies and have been used for investigation of a...
Sheep are a practical model for postmenopausal pathologies and have been used for investigation of a...
The exact relationship between osteoporosis and osteoarthritis is still a matter for debate for many...
AbstractObjective: To examine the effect of topical administration of glyceryl trinitrate (GTN), an ...
Aim: To examine the effect of glyceryl trinitrate (GTN), a nitric oxide (NO) donor compound, on the ...
Ovariectomized (OVX) sheep are now considered to be useful models for a variety of metabolic bone di...
SummaryAimTo examine the effect of glyceryl trinitrate (GTN), a nitric oxide (NO) donor compound, on...
Objective The relationship between the topographical variations in the structural, biochemical and d...
AbstractObjective The relationship between the topographical variations in the structural, biochemic...
AbstractObjectivesOur primary objective was to explore the full potential of the ovine medial menisc...
SummaryAimTo examine the effect of glyceryl trinitrate (GTN), a nitric oxide (NO) donor compound, on...
AbstractObjective The relationship between the topographical variations in the structural, biochemic...
SummaryObjectiveTo examine the effect of oestrogen depletion produced by surgical ovariectomy on the...
SummaryCartilage is a sex-hormone-sensitive tissue but the role of estrogen in the pathogenesis of o...
SummaryCartilage is a sex-hormone-sensitive tissue but the role of estrogen in the pathogenesis of o...
Sheep are a practical model for postmenopausal pathologies and have been used for investigation of a...
Sheep are a practical model for postmenopausal pathologies and have been used for investigation of a...
The exact relationship between osteoporosis and osteoarthritis is still a matter for debate for many...
AbstractObjective: To examine the effect of topical administration of glyceryl trinitrate (GTN), an ...
Aim: To examine the effect of glyceryl trinitrate (GTN), a nitric oxide (NO) donor compound, on the ...
Ovariectomized (OVX) sheep are now considered to be useful models for a variety of metabolic bone di...
SummaryAimTo examine the effect of glyceryl trinitrate (GTN), a nitric oxide (NO) donor compound, on...
Objective The relationship between the topographical variations in the structural, biochemical and d...
AbstractObjective The relationship between the topographical variations in the structural, biochemic...
AbstractObjectivesOur primary objective was to explore the full potential of the ovine medial menisc...
SummaryAimTo examine the effect of glyceryl trinitrate (GTN), a nitric oxide (NO) donor compound, on...
AbstractObjective The relationship between the topographical variations in the structural, biochemic...