Characteristics and treatment pattern of diabetic patients with ACS: A Saudi perspective from the MIDAS Registry

BackgroundMulticenter International Diabetes–Acute Coronary Syndromes (MIDAS) study aimed to monitor the adherence to evidence-based therapy among diabetic patients (DM) with unstable angina or non-ST-segment elevation myocardial infarction (ACS) and to describe the in-hospital outcomes of DM in the setting of ACS. We presente the data of Kingdom of Saudi Arabia (KSA) based on the risk profile of the patients in comparison to the international registry.DesignData of DM patients with ACS who presented at the time of admission to the emergency/coronary care units in 5 hospitals in KSA were extracted from the registry. A total of 3624 patients were enrolled in several countries in Europe and the Middle East and India. The following variables were extracted: ST deviation ⩾0.5mm, positive troponin and, TIMI risk score. The Z test for two proportions was used to compare the KSA values with the international figures. Analysis was done using stata 10. Level of significance was set at 5%.Results“Type II: type I DM ratio” in KSA was comparable to the international ratio (93.65 vs. 93.83). The high risk factors were significantly less prevalent in KSA in comparison to the international Figs. (17% showed significant ST deviation ⩾0.5mm vs 46%, (p=0.005), 40% showed positive troponin vs 70% (p<0.0001) and, 32% showed TIMI risk score >3 in comparison to 62% (p<0.0001).The utilization of GP IIb/IIIa was 18.3% in KSA vs. 37.4% internationally (p=0.046).On the contrary, the utilization of clopidogril/Ticlopidine was 96.8% in KSA vs. 74.7% internationally (p