AbstractObjective: Long-term assessment of the effect of hyaluronan (HA) on the articular cartilage and synovium in an animal knee joint during the development of osteoarthritis (OA).Design: Sixty mature New Zealand white rabbits underwent unilateral anterior cruciate ligament transection (ACLT) and were divided into two groups. Group 1 (SA) received intra-articular injections of 0.3 ml hyaluronan (HA) (i.e., ARTZ, MW: 8×105) beginning 4 weeks after ACLT, once a week for 5 weeks. Group 2 (SV) received injections of the vehicle (phosphate buffered saline) in the same fashion as with the SA group. The contralateral nonoperated knee served as control. All animals were killed 21 weeks after surgery and their knee joints evaluated by gross morph...
The purpose of this study was to determine the effect of one intra-articular injection of hyaluronan...
The purpose of this study was to determine the effect of one intra-articular injection of hyaluronan...
Thirty-two mature female New Zealand White rabbits were immobilised in an aluminium splint on one kn...
AbstractObjective: Long-term assessment of the effect of hyaluronan (HA) on the articular cartilage ...
AbstractBackground: Intra-articular (IA) hyaluronan (HA) injections are approved for the treatment o...
The purpose of this study was to determine the effect of one intra-articular injection of hyaluronan...
The purpose of this study was to determine the effect of one intra-articular injection of hyaluronan...
AbstractObjective The long-term effect of hyaluronan (HA) on meniscus remodeling and articular carti...
ABSTRACTObjective: To evaluate the effects of intra-articular injections of corticosteroids, native ...
SummaryObjectivesWe hypothesized that high-molecular-weight (MW) cross-linked (CL) hyaluronic acid (...
SummaryThe effects of high molecular weight hyaluronan (HA) on cartilage degeneration were investiga...
ABSTRACT Objective: To analyze, from the immunohistochemical perspective, the effects of hyaluronic...
AbstractObjective: The purpose of this study was to determine the effects of intra-articular injecti...
The purpose of this study was to determine the effect of one intra-articular injection of hyaluronan...
The purpose of this study was to determine the effect of one intra-articular injection of hyaluronan...
The purpose of this study was to determine the effect of one intra-articular injection of hyaluronan...
The purpose of this study was to determine the effect of one intra-articular injection of hyaluronan...
Thirty-two mature female New Zealand White rabbits were immobilised in an aluminium splint on one kn...
AbstractObjective: Long-term assessment of the effect of hyaluronan (HA) on the articular cartilage ...
AbstractBackground: Intra-articular (IA) hyaluronan (HA) injections are approved for the treatment o...
The purpose of this study was to determine the effect of one intra-articular injection of hyaluronan...
The purpose of this study was to determine the effect of one intra-articular injection of hyaluronan...
AbstractObjective The long-term effect of hyaluronan (HA) on meniscus remodeling and articular carti...
ABSTRACTObjective: To evaluate the effects of intra-articular injections of corticosteroids, native ...
SummaryObjectivesWe hypothesized that high-molecular-weight (MW) cross-linked (CL) hyaluronic acid (...
SummaryThe effects of high molecular weight hyaluronan (HA) on cartilage degeneration were investiga...
ABSTRACT Objective: To analyze, from the immunohistochemical perspective, the effects of hyaluronic...
AbstractObjective: The purpose of this study was to determine the effects of intra-articular injecti...
The purpose of this study was to determine the effect of one intra-articular injection of hyaluronan...
The purpose of this study was to determine the effect of one intra-articular injection of hyaluronan...
The purpose of this study was to determine the effect of one intra-articular injection of hyaluronan...
The purpose of this study was to determine the effect of one intra-articular injection of hyaluronan...
Thirty-two mature female New Zealand White rabbits were immobilised in an aluminium splint on one kn...