Mirones et al. demonstrate that keratinocytes deficient in VEGF are capable of forming tumors but use a distinct form of aneuploidy and signaling to form tumors. This knowledge is important because inhibitors of VEGF, including bevacizumab (anti-VEGF antibodies) and sorafenib (Braf/VEGFR2 kinase inhibitor), have already entered the clinic. These agents may “remodel” tumor signaling
Different mechanisms of angiogenesis and vasculogenesis are involved in the development of the tumor...
This study examines the role of vascular endothelial growth factor (VEGF) as a therapeutic target in...
International audienceThe anti-VEGF targeted antibody bevacizumab (BVZ) has been approved for treati...
Mirones et al. demonstrate that keratinocytes deficient in VEGF are capable of forming tumors but us...
Vascular endothelial growth factor (VEGF) signaling is critical for tumor angiogenesis. However, the...
SummaryIt is established that tumor cell-derived VEGF acts on endothelial cells to promote angiogene...
The vascular endothelial growth factor (VEGF) family of soluble protein growth factors consists of k...
The vascular endothelial growth factor (VEGF) family of polypeptide growth factors regulates a famil...
In order to grow beyond minimal size and to metastasize, tumors need to induce the growth of new blo...
Receptors for the angiogenic factor VEGF are expressed by tumor cancer cells including melanoma, alt...
AbstractReceptors for the angiogenic factor VEGF are expressed by tumor cancer cells including melan...
This review highlights an emerging function for vascular endothelial growth factor (VEGF) in carcino...
The underlying mechanism by which anti-VEGF agents prolong cancer patient survival is poorly underst...
Vascular endothelial growth factor (VEGF) is known to be a highly specific mitogen for endothelial c...
Angiogenesis is critical during tumour initiation and malignant progression. Different strategies ai...
Different mechanisms of angiogenesis and vasculogenesis are involved in the development of the tumor...
This study examines the role of vascular endothelial growth factor (VEGF) as a therapeutic target in...
International audienceThe anti-VEGF targeted antibody bevacizumab (BVZ) has been approved for treati...
Mirones et al. demonstrate that keratinocytes deficient in VEGF are capable of forming tumors but us...
Vascular endothelial growth factor (VEGF) signaling is critical for tumor angiogenesis. However, the...
SummaryIt is established that tumor cell-derived VEGF acts on endothelial cells to promote angiogene...
The vascular endothelial growth factor (VEGF) family of soluble protein growth factors consists of k...
The vascular endothelial growth factor (VEGF) family of polypeptide growth factors regulates a famil...
In order to grow beyond minimal size and to metastasize, tumors need to induce the growth of new blo...
Receptors for the angiogenic factor VEGF are expressed by tumor cancer cells including melanoma, alt...
AbstractReceptors for the angiogenic factor VEGF are expressed by tumor cancer cells including melan...
This review highlights an emerging function for vascular endothelial growth factor (VEGF) in carcino...
The underlying mechanism by which anti-VEGF agents prolong cancer patient survival is poorly underst...
Vascular endothelial growth factor (VEGF) is known to be a highly specific mitogen for endothelial c...
Angiogenesis is critical during tumour initiation and malignant progression. Different strategies ai...
Different mechanisms of angiogenesis and vasculogenesis are involved in the development of the tumor...
This study examines the role of vascular endothelial growth factor (VEGF) as a therapeutic target in...
International audienceThe anti-VEGF targeted antibody bevacizumab (BVZ) has been approved for treati...