AbstractIn this issue of Neuron, Kaur et al. demonstrate that iron chelation by ferritin transgene or the metal chelator clioquinol prevent oxidative damage and MPTP toxicity in mice. This raises the issue of specific iron chelators or clioquinol for control of oxidative damage in Parkinson's, Alzheimer's, and other neurodegenerative diseases, but not without safety concerns
The homeostasis of transition metal ions is central to many life processes, but the alterations in F...
Iron accumulation and tau protein deposition are pathological features of Alzheimer's (AD) and Parki...
Elevated iron in the SNpc may play a key role in Parkinson's disease (PD) neurodegeneration since dr...
AbstractIn this issue of Neuron, Kaur et al. demonstrate that iron chelation by ferritin transgene o...
AbstractStudies on postmortem brains from Parkinson's patients reveal elevated iron in the substanti...
© 2015 Aguirre et al. This is an open access article distributed under the terms of the Creative Com...
<p>Excessive amounts of labile metals such as iron, zinc, and copper have been found in the brains o...
Artículo de publicación ISIAbundant evidence indicates that iron accumulation, oxidative damage and ...
While the etiology of non-familial Parkinson’s disease (PD) remains unclear, there is evidence that ...
Iron chelation has been introduced as a new therapeutic concept for the treatment of neurodegenerati...
AbstractTransgenic mice developing β-amyloid (Aβ) plaques are advancing experimental treatment strat...
Abstract. Brain iron is an essential nutrient for multiple functions, including gene expression, DNA...
Clioquinol (CQ) is a “metal protein attenuating compound” that crosses the blood-brain barrier and b...
Elevated iron in the SNpc may play a key role in Parkinson’s disease (PD) neurodegeneration since dr...
International audienceIron accumulation has been observed in mouse models and in both sporadic and f...
The homeostasis of transition metal ions is central to many life processes, but the alterations in F...
Iron accumulation and tau protein deposition are pathological features of Alzheimer's (AD) and Parki...
Elevated iron in the SNpc may play a key role in Parkinson's disease (PD) neurodegeneration since dr...
AbstractIn this issue of Neuron, Kaur et al. demonstrate that iron chelation by ferritin transgene o...
AbstractStudies on postmortem brains from Parkinson's patients reveal elevated iron in the substanti...
© 2015 Aguirre et al. This is an open access article distributed under the terms of the Creative Com...
<p>Excessive amounts of labile metals such as iron, zinc, and copper have been found in the brains o...
Artículo de publicación ISIAbundant evidence indicates that iron accumulation, oxidative damage and ...
While the etiology of non-familial Parkinson’s disease (PD) remains unclear, there is evidence that ...
Iron chelation has been introduced as a new therapeutic concept for the treatment of neurodegenerati...
AbstractTransgenic mice developing β-amyloid (Aβ) plaques are advancing experimental treatment strat...
Abstract. Brain iron is an essential nutrient for multiple functions, including gene expression, DNA...
Clioquinol (CQ) is a “metal protein attenuating compound” that crosses the blood-brain barrier and b...
Elevated iron in the SNpc may play a key role in Parkinson’s disease (PD) neurodegeneration since dr...
International audienceIron accumulation has been observed in mouse models and in both sporadic and f...
The homeostasis of transition metal ions is central to many life processes, but the alterations in F...
Iron accumulation and tau protein deposition are pathological features of Alzheimer's (AD) and Parki...
Elevated iron in the SNpc may play a key role in Parkinson's disease (PD) neurodegeneration since dr...
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