AbstractThe obligate aerobic yeast Yarrowia lipolytica is introduced as a powerful new model for the structural and functional analysis of mitochondrial complex I. A brief introduction into the biology and the genetics of this nonconventional yeast is given and the relevant genetic tools that have been developed in recent years are summarized. The respiratory chain of Y. lipolytica contains complexes I–IV, one “alternative” NADH-dehydrogenase (NDH2) and a non-heme alternative oxidase (AOX). Because the NADH binding site of NDH2 faces the mitochondrial intermembrane space rather than the matrix, complex I is an essential enzyme in Y. lipolytica. Nevertheless, complex I deletion strains could be generated by attaching the targeting sequence o...
Numerous heterologous proteins have been successfully produced in Y. lipolytica, a dimorphic yeast w...
AbstractAcyl carrier proteins of mitochondria (ACPMs) are small (∼10 kDa) acidic proteins that are h...
AbstractIn the branched mitochondrial respiratory chain from Yarrowia lipolytica there are two alter...
AbstractMitochondrial proton-translocating NADH-dehydrogenase (complex I) is one of the largest and ...
AbstractWhile diagnosis and genetic analysis of mitochondrial disorders has made remarkable progress...
AbstractProton translocating NADH:ubiquinone oxidoreductase (complex I) is the largest membrane boun...
AbstractIn Yarrowia lipolytica, mitochondria contain a branched respiratory chain constituted by the...
AbstractHere we present a first assessment of the subunit inventory of mitochondrial complex I from ...
AbstractWe have used the obligate aerobic yeast Yarrowia lipolytica to reconstruct and analyse three...
An investigation of the lipid metabolism pathway in the yeast Yarrowia lipolytica was conducted. Yar...
AbstractIn addition to the 14 central subunits, respiratory chain complex I from the aerobic yeast Y...
Oleaginous yeasts are valuable systems for biosustainable production of hydrocarbon-based chemicals....
AbstractNADH:ubiquinone oxidoreductase (complex I) is the largest multiprotein complex of the mitoch...
AbstractUncoupling proteins (UCPs) are mitochondrial carriers distributed throughout the eukaryotic ...
Background: Yarrowia lipolytica is an oleaginous yeast which has emerged as an important microorgani...
Numerous heterologous proteins have been successfully produced in Y. lipolytica, a dimorphic yeast w...
AbstractAcyl carrier proteins of mitochondria (ACPMs) are small (∼10 kDa) acidic proteins that are h...
AbstractIn the branched mitochondrial respiratory chain from Yarrowia lipolytica there are two alter...
AbstractMitochondrial proton-translocating NADH-dehydrogenase (complex I) is one of the largest and ...
AbstractWhile diagnosis and genetic analysis of mitochondrial disorders has made remarkable progress...
AbstractProton translocating NADH:ubiquinone oxidoreductase (complex I) is the largest membrane boun...
AbstractIn Yarrowia lipolytica, mitochondria contain a branched respiratory chain constituted by the...
AbstractHere we present a first assessment of the subunit inventory of mitochondrial complex I from ...
AbstractWe have used the obligate aerobic yeast Yarrowia lipolytica to reconstruct and analyse three...
An investigation of the lipid metabolism pathway in the yeast Yarrowia lipolytica was conducted. Yar...
AbstractIn addition to the 14 central subunits, respiratory chain complex I from the aerobic yeast Y...
Oleaginous yeasts are valuable systems for biosustainable production of hydrocarbon-based chemicals....
AbstractNADH:ubiquinone oxidoreductase (complex I) is the largest multiprotein complex of the mitoch...
AbstractUncoupling proteins (UCPs) are mitochondrial carriers distributed throughout the eukaryotic ...
Background: Yarrowia lipolytica is an oleaginous yeast which has emerged as an important microorgani...
Numerous heterologous proteins have been successfully produced in Y. lipolytica, a dimorphic yeast w...
AbstractAcyl carrier proteins of mitochondria (ACPMs) are small (∼10 kDa) acidic proteins that are h...
AbstractIn the branched mitochondrial respiratory chain from Yarrowia lipolytica there are two alter...