In vitro and in vivo anthelmintic activities of Iris kashmiriana Linn.
- Khan, Abida
- Tak, Hidayatullah
- Nazir, Ruqiaya
- Lone, Bashir A.
DOIAbstract
AbstractIn search of a natural antiparasitic, in vitro and in vivo anthelmintic activities of methanol and aqueous extracts of Iris kashmiriana Linn. rhizome were tested against gastrointestinal nematodes of sheep. A worm motility inhibition assay was used for in vitro study and a faecal egg count reduction assay was used for in vivo study. Crude aqueous extracts of I. kashmiriana exhibited greater anthelmintic activity against Haemonchus contortus than crude methanolic extract (P<0.05). The aqueous extracts of I. kashmiriana resulted in a mean worm motility inhibition of 85.0%, while methanolic extracts resulted in a mean worm motility inhibition of 100.0%. The in vivo anthelmintic activity of aqueous and methanolic extracts of I. kashmiri...
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