Correlation between Glasgow coma scale and Jugular venous oxygen saturation in severe traumatic brain injury

AbstractBackgroundGlasgow Coma Scale (GCS) remains a key measure in neurological assessment after head injury and in most studies classification of the severity of the trauma is still based on the admission GCS.The aim of the workThe aim of the work was to correlate between Jugular venous oxygen saturation (Sjvo2) with GCS in cases with severe traumatic brain injury.Patients and methodsA 44 patients met the inclusion criteria, were included in the present study. They were selected from the neurosurgical and intensive care units at Al-Azhar University hospital during the period from June 2010 till June 2012. All therapeutic interventions were performed in accordance with Guidelines for the Management of Severe Traumatic Brain Injury. The following variables were collected: patients’ demographics, Sjvo2, ICP, MAP, CPP and GCS. All pressures were monitored invasively and with identical transducers connected to monitors, and expressed numerically in mmHg. Measurements were always performed at 8.00 a.m. At the same time, patients were neurologically examined and these data were expressed as GCS score.ResultsThere was statistically significant increase of GCS, MAP, CPP, Sjvo2 and Extended Glasgow Outcome Scale (GOSE) and decrease of ICP in survived in comparison to non-survived cases. In survived cases, there was positive significant correlation between Sjvo2 and GCS, MAP, CPP and GOSE, while there was significant negative correlation with ICT. On the other hand, in non-survived cases, there was only positive moderate, significant correlation between Sjvo2 and GCS. Running simple linear regression analysis, only GCS and Sjvo2 can predict mortality in studied cases.ConclusionResults of the present study proved that, Sjvo2 is proportionally correlated with GCS and both can predict the prognosis of severe traumatic injury