Inhibition of the inflammasome might be beneficial for numerous inflammatory pathologies. In this issue of Immunity, de Almeida et al. (2015) report that the PYRIN domain-only protein (POP1) efficiently inhibits inflammasome activation, identifying it as a pan-inflammasome inhibitor
Item does not contain fulltextInflammasomes are key inducers of inflammation in response to exogenou...
The inflammasome is a cytosolic immune signaling complex that induces inflammation and pyroptosis. I...
The autoinflammatory disorders Muckle-Wells syndrome, familial cold urtecaria and chronic infantile ...
SummaryIn response to infections and tissue damage, ASC-containing inflammasome protein complexes ar...
In response to infections and tissue damage, ASC-containing inflammasome protein complexes are assem...
Inflammasomes are protein platforms linking recognition of microbe, pathogen-associated and damage-a...
Inflammasomes are an innate immune surveillance system that monitors host cells for both pathogen in...
Inhibition of the inflammasome might be beneficial for numerous inflammatory pathologies. In this is...
The innate immune system responds to infection and tissue damage by activating cytosolic sensory com...
Membrane-bound and intracellular immune receptors respond to microbial pathogens by initiating signa...
Proinflammatory caspases play an essential role in innate immune responses to infection by regulatin...
SummaryProinflammatory caspases play an essential role in innate immune responses to infection by re...
Pyrin domain (PYD) proteins have recently emerged as important signaling molecules involved in the d...
Inflammasomes are key regulators of the host response against microbial pathogens, in addition to li...
The pyrin inflammasome has evolved as an innate immune sensor to detect bacterial toxin-induced Rho ...
Item does not contain fulltextInflammasomes are key inducers of inflammation in response to exogenou...
The inflammasome is a cytosolic immune signaling complex that induces inflammation and pyroptosis. I...
The autoinflammatory disorders Muckle-Wells syndrome, familial cold urtecaria and chronic infantile ...
SummaryIn response to infections and tissue damage, ASC-containing inflammasome protein complexes ar...
In response to infections and tissue damage, ASC-containing inflammasome protein complexes are assem...
Inflammasomes are protein platforms linking recognition of microbe, pathogen-associated and damage-a...
Inflammasomes are an innate immune surveillance system that monitors host cells for both pathogen in...
Inhibition of the inflammasome might be beneficial for numerous inflammatory pathologies. In this is...
The innate immune system responds to infection and tissue damage by activating cytosolic sensory com...
Membrane-bound and intracellular immune receptors respond to microbial pathogens by initiating signa...
Proinflammatory caspases play an essential role in innate immune responses to infection by regulatin...
SummaryProinflammatory caspases play an essential role in innate immune responses to infection by re...
Pyrin domain (PYD) proteins have recently emerged as important signaling molecules involved in the d...
Inflammasomes are key regulators of the host response against microbial pathogens, in addition to li...
The pyrin inflammasome has evolved as an innate immune sensor to detect bacterial toxin-induced Rho ...
Item does not contain fulltextInflammasomes are key inducers of inflammation in response to exogenou...
The inflammasome is a cytosolic immune signaling complex that induces inflammation and pyroptosis. I...
The autoinflammatory disorders Muckle-Wells syndrome, familial cold urtecaria and chronic infantile ...
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