AbstractThe mammalian aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates the toxic effects of dioxins and related compounds. Dioxins have been shown to cause a range of neurological defects, but the role of AHR during normal neuronal development is not known. Here we investigate the developmental functions of ahr-1, the Caenorhabditis elegans aryl hydrocarbon receptor homolog. We show that ahr-1:GFP is expressed in a subset of neurons, and we demonstrate that animals lacking ahr-1 function have specific defects in neuronal differentiation, as evidenced by changes in gene expression, aberrant cell migration, axon branching, or supernumerary neuronal processes. In ahr-1-deficient animals, the touch recept...
2,3,7,8-tetrachlorodibenzo-[p]-dioxin (TCDD) is a persistent global pollutant that exhibits a high a...
Some environmental pollutants derived from industrial processes have been suggested to be responsibl...
The Aryl hydrocarbon Receptor (AhR) is a xenobiotic sensor in vertebrates, regulating the metabolism...
AbstractThe mammalian aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor tha...
The mammalian aryl hydrocarbon receptor (AHR) mediates the toxic effects of dioxins and related comp...
The aryl hydrocarbon receptor (or AhR) is a cytoplasmic receptor of pollutants. It translocates into...
The basic helix-loop-helix (bHLH) transcription factors exert multiple functions in mammalian cerebr...
AbstractThe aryl hydrocarbon receptor (AHR) functions in higher organisms in development, metabolism...
Exposure to environmental pollutants and endogenous metabolites that induce aryl hydrocarbon recepto...
2,3,7,8-tetrachlorodibenzo-[p]-dioxin (TCDD) is a persistent global pollutant that exhibits a high a...
2,3,7,8-tetrachlorodibenzo-[p]-dioxin (TCDD) is a persistent global pollutant that exhibits a high a...
2,3,7,8-tetrachlorodibenzo-[p]-dioxin (TCDD) is a persistent global pollutant that exhibits a high a...
AbstractC. elegans ahr-1 is orthologous to the mammalian aryl hydrocarbon receptor, and it functions...
2,3,7,8-tetrachlorodibenzo-[p]-dioxin (TCDD) is a persistent global pollutant that exhibits a high a...
2,3,7,8-tetrachlorodibenzo-[p]-dioxin (TCDD) is a persistent global pollutant that exhibits a high a...
2,3,7,8-tetrachlorodibenzo-[p]-dioxin (TCDD) is a persistent global pollutant that exhibits a high a...
Some environmental pollutants derived from industrial processes have been suggested to be responsibl...
The Aryl hydrocarbon Receptor (AhR) is a xenobiotic sensor in vertebrates, regulating the metabolism...
AbstractThe mammalian aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor tha...
The mammalian aryl hydrocarbon receptor (AHR) mediates the toxic effects of dioxins and related comp...
The aryl hydrocarbon receptor (or AhR) is a cytoplasmic receptor of pollutants. It translocates into...
The basic helix-loop-helix (bHLH) transcription factors exert multiple functions in mammalian cerebr...
AbstractThe aryl hydrocarbon receptor (AHR) functions in higher organisms in development, metabolism...
Exposure to environmental pollutants and endogenous metabolites that induce aryl hydrocarbon recepto...
2,3,7,8-tetrachlorodibenzo-[p]-dioxin (TCDD) is a persistent global pollutant that exhibits a high a...
2,3,7,8-tetrachlorodibenzo-[p]-dioxin (TCDD) is a persistent global pollutant that exhibits a high a...
2,3,7,8-tetrachlorodibenzo-[p]-dioxin (TCDD) is a persistent global pollutant that exhibits a high a...
AbstractC. elegans ahr-1 is orthologous to the mammalian aryl hydrocarbon receptor, and it functions...
2,3,7,8-tetrachlorodibenzo-[p]-dioxin (TCDD) is a persistent global pollutant that exhibits a high a...
2,3,7,8-tetrachlorodibenzo-[p]-dioxin (TCDD) is a persistent global pollutant that exhibits a high a...
2,3,7,8-tetrachlorodibenzo-[p]-dioxin (TCDD) is a persistent global pollutant that exhibits a high a...
Some environmental pollutants derived from industrial processes have been suggested to be responsibl...
The Aryl hydrocarbon Receptor (AhR) is a xenobiotic sensor in vertebrates, regulating the metabolism...