In this issue of Cancer Cell, Murphy et al. describe a mouse model designed to examine the biological effects of different levels of deregulated c-myc expression. They provide evidence that distinct threshold levels of Myc are required for increased proliferation and for apoptosis in different tissues
SummaryDeregulated Myc triggers a variety of intrinsic tumor suppressor programs that serve to restr...
The c-Myc oncoprotein is a master regulator of genes involved in diverse cellular processes. Situate...
c-Myc (hereafter called Myc) belongs to a family of transcription factors that regulates cell growth...
In this issue of Cancer Cell, Murphy et al. describe a mouse model designed to examine the biologica...
The proto-oncogene c-MYC is implicated in various physiological processes-cell growth, proliferation...
MYC is one of the best-studied oncogenes in terms of mouse models of malignancy. MYC overexpression ...
A paradox for cancer biology is represented by the fact that some oncogenes, including c-myc, prov d...
The protein products of many dominant oncogenes are capable of inducing both cell proliferation and ...
The Myc transcription factor activates expression of genes that promote cellular functions such as p...
The potent MYC oncoprotein is deregulated in many human cancers, including breast carcinoma, and is ...
Myc is a pleiotropic basic helix–loop–helix leucine zipper transcription factor that coordinates exp...
One of the enigmas in tumor biology is that different types of cancers are prevalent in different ag...
The c-Myc oncoprotein is a master regulator of genes involved in diverse cellular processes. Situate...
Deregulated Myc triggers a variety of intrinsic tumor suppressor programs that serve to restrain Myc...
One of the enigmas in tumor biology is that different types of cancers are prevalent in different ag...
SummaryDeregulated Myc triggers a variety of intrinsic tumor suppressor programs that serve to restr...
The c-Myc oncoprotein is a master regulator of genes involved in diverse cellular processes. Situate...
c-Myc (hereafter called Myc) belongs to a family of transcription factors that regulates cell growth...
In this issue of Cancer Cell, Murphy et al. describe a mouse model designed to examine the biologica...
The proto-oncogene c-MYC is implicated in various physiological processes-cell growth, proliferation...
MYC is one of the best-studied oncogenes in terms of mouse models of malignancy. MYC overexpression ...
A paradox for cancer biology is represented by the fact that some oncogenes, including c-myc, prov d...
The protein products of many dominant oncogenes are capable of inducing both cell proliferation and ...
The Myc transcription factor activates expression of genes that promote cellular functions such as p...
The potent MYC oncoprotein is deregulated in many human cancers, including breast carcinoma, and is ...
Myc is a pleiotropic basic helix–loop–helix leucine zipper transcription factor that coordinates exp...
One of the enigmas in tumor biology is that different types of cancers are prevalent in different ag...
The c-Myc oncoprotein is a master regulator of genes involved in diverse cellular processes. Situate...
Deregulated Myc triggers a variety of intrinsic tumor suppressor programs that serve to restrain Myc...
One of the enigmas in tumor biology is that different types of cancers are prevalent in different ag...
SummaryDeregulated Myc triggers a variety of intrinsic tumor suppressor programs that serve to restr...
The c-Myc oncoprotein is a master regulator of genes involved in diverse cellular processes. Situate...
c-Myc (hereafter called Myc) belongs to a family of transcription factors that regulates cell growth...