Introduction:Among the driver gene mutations in non–small-cell lung cancer, mutations in epidermal growth factor receptor (EGFR) are the most important because of their predictive role in selecting patients eligible for targeted therapy. Our aim was to study EGFR mutations in a Finnish non–small-cell lung cancer cohort of 528 patients.Methods:Mutation testing was conducted on DNA extracted from paraffin-embedded, formalin-fixed tumor material using the following real-time polymerase chain reaction-based kits: Therascreen EGFR PCR Kit and cobas EGFR Mutation Test.Results:EGFR mutation frequency was 11.4% and all positive cases were adenocarcinomas, of which a majority had an acinar predominant pattern. Mutations were seen significantly more ...
Background: The prevalence of epidermal growth factor receptor (EGFR) mutations in non-small cell lu...
Epidermal growth factor receptor (EGFR) mutations are potential markers driving carcinogenesis, and ...
Introduction:Epidermal growth factor receptor (EGFR) mutations in non–small-cell lung cancer predict...
Introduction:Among the driver gene mutations in non–small-cell lung cancer, mutations in epidermal g...
Objective. The aim of this study was to examine the prevalence of epidermal growth factor receptor (...
Objective. The aim of this study was to examine the prevalence of epidermal growth factor receptor (...
IntroductionLung cancer is the leading cause of cancer-related deaths worldwide. New therapies targe...
Mutations in the receptor of the epidermal growth factor receptor (EGFR) in non-small cell lung canc...
BackgroundThe authors sought to define clinicopathologic features associated with mutations of the e...
Abstract Background A subset of lung cancer patients harbour EGFR somatic mutations in their tumours...
To access publisher's full text version of this article click on the hyperlink belowEpidermal growth...
Introduction:Mutation of the epidermal growth factor receptor (EGFR) gene can predict the efficacy o...
BACKGROUND: Epidermal growth factor receptor (EGFR) T790M mutation drives acquired drug resistance t...
Background: Lung cancer is the leading cause of cancer-related death and one of the most common canc...
Background: Mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EG...
Background: The prevalence of epidermal growth factor receptor (EGFR) mutations in non-small cell lu...
Epidermal growth factor receptor (EGFR) mutations are potential markers driving carcinogenesis, and ...
Introduction:Epidermal growth factor receptor (EGFR) mutations in non–small-cell lung cancer predict...
Introduction:Among the driver gene mutations in non–small-cell lung cancer, mutations in epidermal g...
Objective. The aim of this study was to examine the prevalence of epidermal growth factor receptor (...
Objective. The aim of this study was to examine the prevalence of epidermal growth factor receptor (...
IntroductionLung cancer is the leading cause of cancer-related deaths worldwide. New therapies targe...
Mutations in the receptor of the epidermal growth factor receptor (EGFR) in non-small cell lung canc...
BackgroundThe authors sought to define clinicopathologic features associated with mutations of the e...
Abstract Background A subset of lung cancer patients harbour EGFR somatic mutations in their tumours...
To access publisher's full text version of this article click on the hyperlink belowEpidermal growth...
Introduction:Mutation of the epidermal growth factor receptor (EGFR) gene can predict the efficacy o...
BACKGROUND: Epidermal growth factor receptor (EGFR) T790M mutation drives acquired drug resistance t...
Background: Lung cancer is the leading cause of cancer-related death and one of the most common canc...
Background: Mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EG...
Background: The prevalence of epidermal growth factor receptor (EGFR) mutations in non-small cell lu...
Epidermal growth factor receptor (EGFR) mutations are potential markers driving carcinogenesis, and ...
Introduction:Epidermal growth factor receptor (EGFR) mutations in non–small-cell lung cancer predict...