Asymmetric stem cell division is thought to require precise orientation of the mitotic spindle. However, a recent study in Cell (Yingling et al., 2008) analyzes the role of LIS1 in the developing mouse brain and shows that spindle orientation is more important during early, symmetric progenitor cell divisions than for later asymmetric divisions
Stem cells use mode of cell division, symmetric (SCD) versus asymmetric (ACD), to balance expansion ...
During stem cell divisions, mitotic microtubules do more than just segregate the chromosomes. They a...
SummaryThe importance of asymmetric divisions for stem cell function and maintenance is well establi...
peer reviewedAsymmetric stem cell division is thought to require precise orientation of the mitotic ...
Asymmetric stem cell division is thought to require precise orientation of the mitotic spindle. Howe...
SummaryMitotic spindle orientation and plane of cleavage in mammals is a determinant of whether divi...
In any mitotic cell, the orientation of the mitotic spindle determines the orientation of the cleava...
SummaryIn the developing neocortex, progenitor cells expand through symmetric division before they g...
Cell division orientation during animal development can serve to correctly organize and shape tissue...
Heterozygous LIS1 mutations are responsible for the human neuronal migration disorder lissencephaly....
Neurogenesis is a dynamic process that produces a diverse number of glial and neural cell types from...
SummaryDuring mammalian neurogenesis, progenitor cells can divide with the mitotic spindle oriented ...
Mitotic spindle orientation is crucial for symmetric vs. asymmetric cell division and depends on ast...
The orientation of the mitotic spindle has been proposed to control cell fate choices, tissue archit...
Polarized cortical cues are known to guide spindle movements to dictate division axis and cleavage s...
Stem cells use mode of cell division, symmetric (SCD) versus asymmetric (ACD), to balance expansion ...
During stem cell divisions, mitotic microtubules do more than just segregate the chromosomes. They a...
SummaryThe importance of asymmetric divisions for stem cell function and maintenance is well establi...
peer reviewedAsymmetric stem cell division is thought to require precise orientation of the mitotic ...
Asymmetric stem cell division is thought to require precise orientation of the mitotic spindle. Howe...
SummaryMitotic spindle orientation and plane of cleavage in mammals is a determinant of whether divi...
In any mitotic cell, the orientation of the mitotic spindle determines the orientation of the cleava...
SummaryIn the developing neocortex, progenitor cells expand through symmetric division before they g...
Cell division orientation during animal development can serve to correctly organize and shape tissue...
Heterozygous LIS1 mutations are responsible for the human neuronal migration disorder lissencephaly....
Neurogenesis is a dynamic process that produces a diverse number of glial and neural cell types from...
SummaryDuring mammalian neurogenesis, progenitor cells can divide with the mitotic spindle oriented ...
Mitotic spindle orientation is crucial for symmetric vs. asymmetric cell division and depends on ast...
The orientation of the mitotic spindle has been proposed to control cell fate choices, tissue archit...
Polarized cortical cues are known to guide spindle movements to dictate division axis and cleavage s...
Stem cells use mode of cell division, symmetric (SCD) versus asymmetric (ACD), to balance expansion ...
During stem cell divisions, mitotic microtubules do more than just segregate the chromosomes. They a...
SummaryThe importance of asymmetric divisions for stem cell function and maintenance is well establi...
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