Although it is well appreciated that autophagy begins with phagophore formation and expansion through lipid acquisition to become the autophagosome, this process remains poorly understood, with the source of autophagosome membrane controversial. Reporting recently in Nature, Hamasaki et al. (2013) suggest that the ER-mitochondria contact sites are involved in phagophore assembly
The membrane origins of autophagosomes have been a key unresolved question in the field. The earlies...
Lilith VJC Mannack, Jon D Lane Cell Biology Laboratories, School of Biochemistry, University of Bris...
AbstractMacro-autophagy (autophagy) is a conserved catabolic pathway for the degradation of cytoplas...
Although it is well appreciated that autophagy begins with phagophore formation and expansion throug...
Autophagosomes are large double-membrane vesicles that enclose cytoplasmic components targeting them...
Autophagy begins with the nucleation of phagophores, which then expand to give rise to the double-me...
Autophagy is a catabolic intracellular process highly conserved among eukaryotes. During this proces...
The de novo generation of double-membrane autophagosomes is the hallmark of autophagy. The initial m...
Autophagy–the lysosomal degradation of cytoplasm–plays a central role in cellular homeostasis and pr...
Autophagy is a highly conserved pathway that is essential for cell survival and is implicated in sev...
Autophagy is a conserved catabolic process critical for cell homeostasis with broad implications for...
textabstractAutophagosomes, the hallmark of autophagy, are double-membrane vesicles sequestering cyt...
<p>A. The process of autophagy. Cytoplasmic material (here a bacterium) is targeted by an isolation ...
Autophagy is molecular machinery for “self-digestion” in cells. It is a highly conserved process for...
Today, more than 50 years after the discovery of autophagy, the origin of the autophagosomal membran...
The membrane origins of autophagosomes have been a key unresolved question in the field. The earlies...
Lilith VJC Mannack, Jon D Lane Cell Biology Laboratories, School of Biochemistry, University of Bris...
AbstractMacro-autophagy (autophagy) is a conserved catabolic pathway for the degradation of cytoplas...
Although it is well appreciated that autophagy begins with phagophore formation and expansion throug...
Autophagosomes are large double-membrane vesicles that enclose cytoplasmic components targeting them...
Autophagy begins with the nucleation of phagophores, which then expand to give rise to the double-me...
Autophagy is a catabolic intracellular process highly conserved among eukaryotes. During this proces...
The de novo generation of double-membrane autophagosomes is the hallmark of autophagy. The initial m...
Autophagy–the lysosomal degradation of cytoplasm–plays a central role in cellular homeostasis and pr...
Autophagy is a highly conserved pathway that is essential for cell survival and is implicated in sev...
Autophagy is a conserved catabolic process critical for cell homeostasis with broad implications for...
textabstractAutophagosomes, the hallmark of autophagy, are double-membrane vesicles sequestering cyt...
<p>A. The process of autophagy. Cytoplasmic material (here a bacterium) is targeted by an isolation ...
Autophagy is molecular machinery for “self-digestion” in cells. It is a highly conserved process for...
Today, more than 50 years after the discovery of autophagy, the origin of the autophagosomal membran...
The membrane origins of autophagosomes have been a key unresolved question in the field. The earlies...
Lilith VJC Mannack, Jon D Lane Cell Biology Laboratories, School of Biochemistry, University of Bris...
AbstractMacro-autophagy (autophagy) is a conserved catabolic pathway for the degradation of cytoplas...
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