AbstractSerum total immunoglobulin (G, A, M and E) and IgG subclass levels were studied in 23 patients with brittle asthma, 23 age- and sex-matched patients with mild asthma and 33 patients with recurrent infective exacerbations of their asthma. Patients with brittle asthma showed significantly reduced levels of IgG (mean ± SD, 8·8 ± 3·3 g l−1) compared to patients with mild asthma (11·0 ± 2·5 g l−1) (P<0·008) with further significant reductions in the brittle compared to the mild group in IgG1 (5·2 vs 6·3, P=0·035), IgG2 (2·4 vs 3·25, P<0·006), IgG3 (0·39 vs 0·55, P<0·05) and IgA (1·91 vs 2·38, P<0·03). There were no significant differences between the brittle group and the group with recurrent infective exacerbations for any parameter, bu...
To clarify the pathogenesis of asthma especially intractable asthma, we measured the serum levels of...
Background and aim: Asthma is a chronic inflammatory airway disease mediated by immunologic mechanis...
Of 32 unrelated children with serum IgE > 1,000 U/ml, 17 were found to have infection proneness acco...
AbstractSerum total immunoglobulin (G, A, M and E) and IgG subclass levels were studied in 23 patien...
IgG subclass concentrations were measured in 25 extrinsic asthmatic children because IgG subclass de...
Serum immunoglobulins including IgG subclasses were measured in 73 unselected children with asthma. ...
About 5% of asthmatics do not behave like ‘classical’ asthmatics and may not respond adequately to c...
The immediate asthmatic response is mainly induced by IgE-dependent mechanisms. However, the late as...
Immunoglobulin classes which induce a non-immediate asthmatic response (non-IAR) in the case of low ...
Background/Aims Primary immunodef iciency (PID) is a serious comorbid condition in adult asthmatics ...
There are many problems in intractable asthmatics, such as corticosteroid dependency. The clinical c...
To clarify the action of IgG antibody on basophils in intractable asthmatics, morphological changes,...
We studied the incidence of IgG subclass deficiency in children with recurrent bronchitis. Recurrent...
(Cp) biomarkers have been associated with asthma but Cp-specific IgE (Cp IgE) has not been investig...
The similarities between the clinical characteristics of instractable asthma and attacks of late ast...
To clarify the pathogenesis of asthma especially intractable asthma, we measured the serum levels of...
Background and aim: Asthma is a chronic inflammatory airway disease mediated by immunologic mechanis...
Of 32 unrelated children with serum IgE > 1,000 U/ml, 17 were found to have infection proneness acco...
AbstractSerum total immunoglobulin (G, A, M and E) and IgG subclass levels were studied in 23 patien...
IgG subclass concentrations were measured in 25 extrinsic asthmatic children because IgG subclass de...
Serum immunoglobulins including IgG subclasses were measured in 73 unselected children with asthma. ...
About 5% of asthmatics do not behave like ‘classical’ asthmatics and may not respond adequately to c...
The immediate asthmatic response is mainly induced by IgE-dependent mechanisms. However, the late as...
Immunoglobulin classes which induce a non-immediate asthmatic response (non-IAR) in the case of low ...
Background/Aims Primary immunodef iciency (PID) is a serious comorbid condition in adult asthmatics ...
There are many problems in intractable asthmatics, such as corticosteroid dependency. The clinical c...
To clarify the action of IgG antibody on basophils in intractable asthmatics, morphological changes,...
We studied the incidence of IgG subclass deficiency in children with recurrent bronchitis. Recurrent...
(Cp) biomarkers have been associated with asthma but Cp-specific IgE (Cp IgE) has not been investig...
The similarities between the clinical characteristics of instractable asthma and attacks of late ast...
To clarify the pathogenesis of asthma especially intractable asthma, we measured the serum levels of...
Background and aim: Asthma is a chronic inflammatory airway disease mediated by immunologic mechanis...
Of 32 unrelated children with serum IgE > 1,000 U/ml, 17 were found to have infection proneness acco...