Homeostasis and repair of different lung compartments require the selective activation of specific progenitor/stem cells and their regulated differentiation to yield cell types that fulfill specialized regional functions. In this issue of Cell Stem Cell, Pardo-Saganta et al. (2015) identify Notch signaling as a determinant of basal cell heterogeneity and fate decisions in pseudostratified airways
Little is known about the mechanisms by which the lung epithelial progenitors are initially patterne...
The airways are conduits that transport atmospheric oxygen to the distal alveolus. Normally, airway ...
O epitélio pulmonar é formado por uma grande diversidade celular, que incluí: células secretoras, ci...
Homeostasis and repair of different lung compartments require the selective activation of specific p...
Homeostasis and repair of different lung compartments require the selective activation of specific p...
Airway epithelium is maintained by basal cells, but the mechanisms responsible for repair are poorly...
Basal cells are multipotent airway progenitors that generate distinct epithelial cell phenotypes cru...
Although there is accumulated evidence of a role for Notch in the developing lung, it is still uncle...
SummaryFollowing injury, stem cells restore normal tissue architecture by producing the proper numbe...
Although there is accumulated evidence of a role for Notch in the developing lung, it is still uncle...
The epithelium lining the airways of the adult human lung is composed of ciliated and secretory cell...
SummaryThe epithelium lining the airways of the adult human lung is composed of ciliated and secreto...
Notch signaling is an evolutionarily conserved cell–cell communication mechanism that plays a key ro...
Human lung development is a complex process guided by specific tissue interactions and cellular sign...
Tissue resident stem cells are capable of remarkable plasticity in areas of tissue damage, where inf...
Little is known about the mechanisms by which the lung epithelial progenitors are initially patterne...
The airways are conduits that transport atmospheric oxygen to the distal alveolus. Normally, airway ...
O epitélio pulmonar é formado por uma grande diversidade celular, que incluí: células secretoras, ci...
Homeostasis and repair of different lung compartments require the selective activation of specific p...
Homeostasis and repair of different lung compartments require the selective activation of specific p...
Airway epithelium is maintained by basal cells, but the mechanisms responsible for repair are poorly...
Basal cells are multipotent airway progenitors that generate distinct epithelial cell phenotypes cru...
Although there is accumulated evidence of a role for Notch in the developing lung, it is still uncle...
SummaryFollowing injury, stem cells restore normal tissue architecture by producing the proper numbe...
Although there is accumulated evidence of a role for Notch in the developing lung, it is still uncle...
The epithelium lining the airways of the adult human lung is composed of ciliated and secretory cell...
SummaryThe epithelium lining the airways of the adult human lung is composed of ciliated and secreto...
Notch signaling is an evolutionarily conserved cell–cell communication mechanism that plays a key ro...
Human lung development is a complex process guided by specific tissue interactions and cellular sign...
Tissue resident stem cells are capable of remarkable plasticity in areas of tissue damage, where inf...
Little is known about the mechanisms by which the lung epithelial progenitors are initially patterne...
The airways are conduits that transport atmospheric oxygen to the distal alveolus. Normally, airway ...
O epitélio pulmonar é formado por uma grande diversidade celular, que incluí: células secretoras, ci...