AbstractObjectivesLow-molecular-weight (LMW) substances are known to be causative agents of occupational asthma (OA) and occupational rhinitis (OR). Although most LMW substances are irritants or allergens, some can cause immediate type immunoglobulin E (IgE)-mediated allergic reactions. Trimellitic anhydride (TMA) is one such LMW substance, which is known as an immunological sensitizer. However, the exact molecular biological details of the effects of TMA remain unclear.MethodsWe measured the β-hexosaminidase release from mast cells after directly exposing the cells to various LMW substances. The tyrosine phosphorylation of whole cellular molecules and the phosphorylation of extracellular signal-regulated kinase (ERK) were assessed by immun...
We describe seven women with asthma induced by occupational exposure to an acid anhydride, tetrachlo...
We describe seven women with asthma induced by occupational exposure to an acid anhydride, tetrachlo...
BACKGROUND: The pathogenesis and the pathologic alterations of occupational asthma are similar to th...
Objectives: Low-molecular-weight (LMW) substances are known to be causative agents of occupational a...
AbstractObjectivesLow-molecular-weight (LMW) substances are known to be causative agents of occupati...
Understanding the pathogenesis and working mechanisms of occupational asthma (OA) is crucial towards...
Occupational exposure to low molecular weight chemicals, like trimellitic anhydride (TMA), can resul...
We have studied asthma caused by inhaled acid anhydrides as a model of hapten-induced airway hyperre...
Acid anhydrides (AA) are reactive low molecular weight chemicals used in the manufacture of plastici...
Trimellitic anhydride (TMA) is one of many low molecular weight compounds known to cause occupationa...
Occupational exposure to certain acid anhydrides, including trimellitic anhydride (TMA), maleic anhy...
Occupational exposure to low molecular weight chemicals, like trimellitic anhydride (TMA), can resul...
AbstractOccupational immunological lung disease, due to low molecular weight, reactive chemicals suc...
To contribute to the hazard identification of low molecular weight (LMW) respiratory allergens, resp...
The role of immunoglobulin (Ig)-E in occupational asthma (OA) due to low molecular weight (LMW) agen...
We describe seven women with asthma induced by occupational exposure to an acid anhydride, tetrachlo...
We describe seven women with asthma induced by occupational exposure to an acid anhydride, tetrachlo...
BACKGROUND: The pathogenesis and the pathologic alterations of occupational asthma are similar to th...
Objectives: Low-molecular-weight (LMW) substances are known to be causative agents of occupational a...
AbstractObjectivesLow-molecular-weight (LMW) substances are known to be causative agents of occupati...
Understanding the pathogenesis and working mechanisms of occupational asthma (OA) is crucial towards...
Occupational exposure to low molecular weight chemicals, like trimellitic anhydride (TMA), can resul...
We have studied asthma caused by inhaled acid anhydrides as a model of hapten-induced airway hyperre...
Acid anhydrides (AA) are reactive low molecular weight chemicals used in the manufacture of plastici...
Trimellitic anhydride (TMA) is one of many low molecular weight compounds known to cause occupationa...
Occupational exposure to certain acid anhydrides, including trimellitic anhydride (TMA), maleic anhy...
Occupational exposure to low molecular weight chemicals, like trimellitic anhydride (TMA), can resul...
AbstractOccupational immunological lung disease, due to low molecular weight, reactive chemicals suc...
To contribute to the hazard identification of low molecular weight (LMW) respiratory allergens, resp...
The role of immunoglobulin (Ig)-E in occupational asthma (OA) due to low molecular weight (LMW) agen...
We describe seven women with asthma induced by occupational exposure to an acid anhydride, tetrachlo...
We describe seven women with asthma induced by occupational exposure to an acid anhydride, tetrachlo...
BACKGROUND: The pathogenesis and the pathologic alterations of occupational asthma are similar to th...