The nature and functions of cells creating hematopoietic niches during inflammation remain incompletely understood. In this issue of Immunity, Kwak et al. (2015) reveal that myeloid cell-produced reactive oxygen species stimulate proliferation of myeloid progenitors establishing an additional mechanism to regulate hematopoiesis
Loss-of-function studies have shown that cyto-kines have specific roles in maintaining lineage outpu...
textabstractHematopoiesis is the formation of blood cellular components. In mammalian embryonic dev...
Trained innate immunity fosters a sustained favorable response of myeloid cells to a secondary chall...
The nature and functions of cells creating hematopoietic niches during inflammation remain incomplet...
SummaryThe cellular mechanisms controlling infection-induced emergency granulopoiesis are poorly def...
The cellular mechanisms controlling infection-induced emergency granulopoiesis are poorly defined. H...
Both microbial infection and sterile inflammation augment bone marrow (BM) neutrophil production, bu...
An intact and fully functional innate immune system is critical in the defense against pathogens. In...
Innate myeloid immune cells, and neutrophils in particular, serve as first line of defense against p...
Reactive oxygen species (ROS) are a heterogeneous group of molecules that are generated by mature my...
In a healthy adult person, almost 1011 - 1012 new blood cells are generated daily in order to mainta...
PURPOSE OF REVIEW: During severe systemic infection, steady-state hematopoiesis is switched to deman...
textabstractThe word hematopoiesis is derived from the greek words, haima meaning blood and poiesis ...
Trained innate immunity fosters a sustained favorable response of myeloid cells to a secondary chall...
SummaryDuring an infection, the body increases the output of mature immune cells in order to fight o...
Loss-of-function studies have shown that cyto-kines have specific roles in maintaining lineage outpu...
textabstractHematopoiesis is the formation of blood cellular components. In mammalian embryonic dev...
Trained innate immunity fosters a sustained favorable response of myeloid cells to a secondary chall...
The nature and functions of cells creating hematopoietic niches during inflammation remain incomplet...
SummaryThe cellular mechanisms controlling infection-induced emergency granulopoiesis are poorly def...
The cellular mechanisms controlling infection-induced emergency granulopoiesis are poorly defined. H...
Both microbial infection and sterile inflammation augment bone marrow (BM) neutrophil production, bu...
An intact and fully functional innate immune system is critical in the defense against pathogens. In...
Innate myeloid immune cells, and neutrophils in particular, serve as first line of defense against p...
Reactive oxygen species (ROS) are a heterogeneous group of molecules that are generated by mature my...
In a healthy adult person, almost 1011 - 1012 new blood cells are generated daily in order to mainta...
PURPOSE OF REVIEW: During severe systemic infection, steady-state hematopoiesis is switched to deman...
textabstractThe word hematopoiesis is derived from the greek words, haima meaning blood and poiesis ...
Trained innate immunity fosters a sustained favorable response of myeloid cells to a secondary chall...
SummaryDuring an infection, the body increases the output of mature immune cells in order to fight o...
Loss-of-function studies have shown that cyto-kines have specific roles in maintaining lineage outpu...
textabstractHematopoiesis is the formation of blood cellular components. In mammalian embryonic dev...
Trained innate immunity fosters a sustained favorable response of myeloid cells to a secondary chall...