Efficacy and Safety of Great Saphenous Vein Sclerotherapy Using Standardised Polidocanol Foam (ESAF): A Randomised Controlled Multicentre Clinical Trial
- Rabe, E.
- Otto, J.
- Schliephake, D.
- Pannier, F.
DOIAbstract
AimTo assess the safety and efficacy of sclerotherapy of the great saphenous vein (GSV) comparing standardised polidocanol foam to liquid polidocanol in a randomised controlled trial (RCT).MethodsA multicentre randomised controlled clinical trial was carried out in which saphenous trunks were treated by sclerotherapy. 106 patients with primary varicose veins due to an incompetent GSV were treated with either standardised 3% polidocanol foam or 3% liquid polidocanol. The primary efficacy criterion was elimination of reflux (<0.5 sec) measured 3cm below the sapheno-femoral junction (SFJ) by duplex ultrasonography 3 months after the last injection.ResultsA significantly greater number of patients were successfully treated by foam sclerotherapy...
Add to ORKG