AbstractLeukemic cells and human hematopoietic progenitor cells expressing CD44 receptors have the ability to attach and roll on hyaluronan. We investigated quantitatively the adhesion behavior of leukemic cell lines and hematopoietic progenitor cells on thin films of the polysaccharides hyaluronan and alginate in a microfluidic system. An applied flow enhances the interaction between CD44-positive cells and hyaluronan if a threshold shear stress of 0.2 dyn/cm2 is exceeded. At shear stress ∼1 dyn/cm2, the cell rolling speed reaches a maximum of 15 μm/s. Leukemic Jurkat and Kasumi-1 cells lacking CD44-expression showed no adhesion or rolling on the polysaccharides whereas the CD44-expressing leukemic cells KG-1a, HL-60, K-562, and hematopoie...
Abstract: Endothelial progenitor cells (EPCs) circulating in peripheral blood migrate towards target...
Cell-cell and cell-glycocalyx interactions under flow are important for the behaviour of circulating...
Acute myeloid leukaemia is a malicious disease. Although the initial chemotherapeutic treatment ofte...
Leukemic cells and human hematopoietic progenitor cells expressing CD44 receptors have the ability t...
AbstractLeukemic cells and human hematopoietic progenitor cells expressing CD44 receptors have the a...
We previously demonstrated that leukemia cell lines expressing CD44 and hematopoietic progenitor cel...
As a known receptor-ligand pair for mediating cell-cell or cell-extracellular matrix adhesions, clus...
Hematopoietic stem and progenitor cells (HSPC) give rise to all mature blood cells and have a range ...
Hematopoietic stem/progenitor cell (HSPC) homing occurs via cell adhesion mediated by spatiotemporal...
Adhesive interactions between CD34(+) hematopoietic progenitor cells (HPC) and bone marrow stroma ar...
CD44 is a widely expressed cell adhesion molecule that binds to the extracellular matrix component, ...
Cell rolling adhesion is a mode of passive directional migration under flow used by a variety of pro...
UnlabelledThe high-molecular-weight glycosaminoglycan, hyaluronic acid (HA), makes up a significant ...
With the rapidly growing interest in the use of mesenchymal stromal cells (MSCs) for cell therapy an...
AbstractLate outgrowth endothelial progenitor cells (EPCs) represent a promising cell source for rap...
Abstract: Endothelial progenitor cells (EPCs) circulating in peripheral blood migrate towards target...
Cell-cell and cell-glycocalyx interactions under flow are important for the behaviour of circulating...
Acute myeloid leukaemia is a malicious disease. Although the initial chemotherapeutic treatment ofte...
Leukemic cells and human hematopoietic progenitor cells expressing CD44 receptors have the ability t...
AbstractLeukemic cells and human hematopoietic progenitor cells expressing CD44 receptors have the a...
We previously demonstrated that leukemia cell lines expressing CD44 and hematopoietic progenitor cel...
As a known receptor-ligand pair for mediating cell-cell or cell-extracellular matrix adhesions, clus...
Hematopoietic stem and progenitor cells (HSPC) give rise to all mature blood cells and have a range ...
Hematopoietic stem/progenitor cell (HSPC) homing occurs via cell adhesion mediated by spatiotemporal...
Adhesive interactions between CD34(+) hematopoietic progenitor cells (HPC) and bone marrow stroma ar...
CD44 is a widely expressed cell adhesion molecule that binds to the extracellular matrix component, ...
Cell rolling adhesion is a mode of passive directional migration under flow used by a variety of pro...
UnlabelledThe high-molecular-weight glycosaminoglycan, hyaluronic acid (HA), makes up a significant ...
With the rapidly growing interest in the use of mesenchymal stromal cells (MSCs) for cell therapy an...
AbstractLate outgrowth endothelial progenitor cells (EPCs) represent a promising cell source for rap...
Abstract: Endothelial progenitor cells (EPCs) circulating in peripheral blood migrate towards target...
Cell-cell and cell-glycocalyx interactions under flow are important for the behaviour of circulating...
Acute myeloid leukaemia is a malicious disease. Although the initial chemotherapeutic treatment ofte...