0008: Anxiety and depressive symptoms after acute coronary syndrome: prevalence, evolution and predictive factors

Anxiety and depressive symptoms after acute coronary syndrome (ACS) are associated with increased mortality and morbidity, more random cardiac rehabilitation, unhealthy behaviours. The aim of this study was to determine prevalence of these symptoms after ACS, and associated factors.During 6 months, all patients admitted to the Hospital of Reims for ACS were included. Hospital Anxiety and Depression Score (HADS) was used to screen anxiodepressive symptoms during initial hospitalization and 3 months later. The analysis focused on socio-demographic, clinico-biological and therapeutic data.We included 101 patients. 40,6% had anxiety and depressive symptoms on admission and 41,6% at 3 months. Factors associated with a high persistent 3 month score were: initial HADS score (r = 0,81 p<0.001), history of depression (OR 14,1; CI95% 1,7-42,4 p<0,001), history of coronary heart disease (OR 5,8; 95% CI95% 1,7-19,6 p<0,001), young age (54,4 years ± 10,9 p 0,039), social isolation (OR 12,5; CI95% 4,2-37,3 p<, 001), smoking (OR 8,7; CI95% 3,5-21,7 p<0.001), physical inactivity (OR 5,1; CI95% 2, 3-10,9 p <0.001), early ventricular arrhythmias (OR 13,5; CI95% 5,1-35,9 p<0,001). Also high C-reactive protein (OR 11,8; p< 0,001), a low HDL-cholesterol (mean 0,4g/L p < 0.001), and high level of liver enzyme (OR 0,3; p