AbstractBackground: Antiamoebin is a member of the peptaibol family of polypeptides and has a unique antibiotic activity: it acts as an antiamoebic agent, but does not effectively haemolyze erythrocytes even though it does exhibit membrane-modifying activity.Results: The structure of antiamoebin I has been determined by X-ray crystallography at 1.4 å resolution. The molecule forms a helical structure, which, as a result of the presence of a number of proline and hydroxyproline residues, has a deep bend in the middle. Circular dichroism spectroscopy, single-channel conductance studies and fluorescence diffusion studies suggest a mode of ion transport that is entirely different from that of the other two members of the peptaibol family (alame...
Cationic antimicrobial peptides are a class of small, positively charged peptides known for their b...
Alamethicin is a transmembrane ion channel at low concentration, and a lytic agent of cell membrane ...
Innate antimicrobial peptides have served as the first line of defense against pathogens throughout ...
AbstractBackground: Antiamoebin is a member of the peptaibol family of polypeptides and has a unique...
AbstractAntiamoebin is a 16-residue polypeptide whose crystal structure and lytic activity in membra...
Membrane channels facilitate the flow of ions across biological membranes, a process which is import...
Crystals of an ion-channel-forming peptaibol peptide in a partial membrane environment have been obt...
ABSTRACT Antiamoebin I is a membrane-active peptaibol produced by fungi of the species Emericellopsi...
AbstractAntiamoebin I is a membrane-active peptaibol produced by fungi of the species Emericellopsis...
Peptaibols are peptide antibiotics that typically feature an N-terminal acetyl cap, a C-terminal ami...
ABSTRACT: The conformations of the 16-residue fungal peptide antiamoebin I (Ac-Phe-Aib-Aib-Aib-D-Iva...
Peptaibol antibiotics are membrane-active linear peptides of fungal origin that are characterized by...
Peptaibols are naturally-occurring, antimicrobial peptides endowed with well-defined helical conform...
AbstractPermeabilization of the phospholipid membrane, induced by the antibiotic peptides zervamicin...
AbstractAntimicrobial peptides (AMPs) are small, usually cationic peptides, which permeabilize bacte...
Cationic antimicrobial peptides are a class of small, positively charged peptides known for their b...
Alamethicin is a transmembrane ion channel at low concentration, and a lytic agent of cell membrane ...
Innate antimicrobial peptides have served as the first line of defense against pathogens throughout ...
AbstractBackground: Antiamoebin is a member of the peptaibol family of polypeptides and has a unique...
AbstractAntiamoebin is a 16-residue polypeptide whose crystal structure and lytic activity in membra...
Membrane channels facilitate the flow of ions across biological membranes, a process which is import...
Crystals of an ion-channel-forming peptaibol peptide in a partial membrane environment have been obt...
ABSTRACT Antiamoebin I is a membrane-active peptaibol produced by fungi of the species Emericellopsi...
AbstractAntiamoebin I is a membrane-active peptaibol produced by fungi of the species Emericellopsis...
Peptaibols are peptide antibiotics that typically feature an N-terminal acetyl cap, a C-terminal ami...
ABSTRACT: The conformations of the 16-residue fungal peptide antiamoebin I (Ac-Phe-Aib-Aib-Aib-D-Iva...
Peptaibol antibiotics are membrane-active linear peptides of fungal origin that are characterized by...
Peptaibols are naturally-occurring, antimicrobial peptides endowed with well-defined helical conform...
AbstractPermeabilization of the phospholipid membrane, induced by the antibiotic peptides zervamicin...
AbstractAntimicrobial peptides (AMPs) are small, usually cationic peptides, which permeabilize bacte...
Cationic antimicrobial peptides are a class of small, positively charged peptides known for their b...
Alamethicin is a transmembrane ion channel at low concentration, and a lytic agent of cell membrane ...
Innate antimicrobial peptides have served as the first line of defense against pathogens throughout ...