AbstractProteins that specifically bind the single-stranded overhang at the ends of telomeres have been identified in a wide range of eukaryotes and play pivotal roles in chromosome end protection and telomere length regulation. Here we summarize recent findings regarding the functions of POT1 proteins in vertebrates and discuss the functional evolution of POT1 proteins following gene duplication in protozoa, plants, nematodes and mice
The telomere is a conserved nucleoprotein structure at the ends of eukaryotic chromosomes. It is ess...
<p>Telomeres are DNA-protein structures that protect eukaryotic chromosome ends from illegitimate re...
Gene duplication is a major driving force in genome evolution. Here, we explore the nature and origi...
AbstractProteins that specifically bind the single-stranded overhang at the ends of telomeres have b...
SummaryHuman telomeres are protected by shelterin, a complex that includes the POT1 single-stranded ...
The single-stranded telomeric DNA binding protein POT1 protects mammalian chromosome ends from the A...
Pot1 is a conserved single-stranded DNA binding protein with crucial functions in the protection of ...
The evolutionarily conserved POT1 protein binds single-stranded G-rich telomeric DNA and has been im...
The evolutionarily conserved POT1 protein binds single-stranded G-rich telomeric DNA and has been im...
The mammalian protein POT1 binds to telomeric single-stranded DNA (ssDNA), protecting chromosome end...
Eukaryotic chromosomes typically end in 3′ telomeric overhangs. The safeguarding of telomeric single...
Deleting the OB folds encoding the telomeric single-stranded DNA (ssDNA)-binding activity of the hum...
SummaryThe terminal t-loop structure adopted by mammalian telomeres is thought to prevent telomeres ...
Telomeres define the ends of linear eukaryotic chromosomes and are required for genome maintenance a...
© The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biolo...
The telomere is a conserved nucleoprotein structure at the ends of eukaryotic chromosomes. It is ess...
<p>Telomeres are DNA-protein structures that protect eukaryotic chromosome ends from illegitimate re...
Gene duplication is a major driving force in genome evolution. Here, we explore the nature and origi...
AbstractProteins that specifically bind the single-stranded overhang at the ends of telomeres have b...
SummaryHuman telomeres are protected by shelterin, a complex that includes the POT1 single-stranded ...
The single-stranded telomeric DNA binding protein POT1 protects mammalian chromosome ends from the A...
Pot1 is a conserved single-stranded DNA binding protein with crucial functions in the protection of ...
The evolutionarily conserved POT1 protein binds single-stranded G-rich telomeric DNA and has been im...
The evolutionarily conserved POT1 protein binds single-stranded G-rich telomeric DNA and has been im...
The mammalian protein POT1 binds to telomeric single-stranded DNA (ssDNA), protecting chromosome end...
Eukaryotic chromosomes typically end in 3′ telomeric overhangs. The safeguarding of telomeric single...
Deleting the OB folds encoding the telomeric single-stranded DNA (ssDNA)-binding activity of the hum...
SummaryThe terminal t-loop structure adopted by mammalian telomeres is thought to prevent telomeres ...
Telomeres define the ends of linear eukaryotic chromosomes and are required for genome maintenance a...
© The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biolo...
The telomere is a conserved nucleoprotein structure at the ends of eukaryotic chromosomes. It is ess...
<p>Telomeres are DNA-protein structures that protect eukaryotic chromosome ends from illegitimate re...
Gene duplication is a major driving force in genome evolution. Here, we explore the nature and origi...