In this issue of Immunity, Metkar et al. (2008) present evidence that granzyme A plays a role in inflammatory signaling and that contrary to previous studies, it is incapable of inducing target cell death. The work challenges us to reconsider the broader biological roles of all the granzymes
Granzyme A (GzmA) is considered a major proapoptotic protease. We have discovered that GzmA-induced ...
Cytotoxic lymphocytes rapidly respond and destroy both malignant cells and cells infected with intra...
In this issue of Immunity, Devadas and colleagues (2006) reveal that granzyme B, long known as a med...
In this issue of Immunity, Metkar et al. (2008) present evidence that granzyme A plays a role in inf...
The cytotoxic properties of granzymes are well established, though recent publications suggest addit...
Granzymes are a family of serine proteases stored in granules inside cytotoxic cells of the immune s...
Granzymes (Grs) are serine proteases mainly produced by cytotoxic lymphocytes and are traditionally ...
Granzyme A: cell death–inducing protease, proinflammatory agent, or both? We recently showed that gr...
It has been well established that granzymes released by cytotoxic lymphocytes induce cell death in v...
Cytotoxic lymphocytes are the key effector immune cells that deal with tumor cells and virus-infecte...
THESIS 9588Excerpt from introduction: In all vertebrate organisms a properly functioning immune syst...
Lymphocyte perforin and serine protease granzymes are well-recognized extrinsic mediators of apoptos...
Inflammation is strictly interconnected to anti-inflammatory mechanisms to maintain tissue homeostas...
The cytotoxic cell granule secretory pathway is viewed as indispensable for eliminating tumor and vi...
SummaryGranzyme A (GzmA) is considered a major proapoptotic protease. We have discovered that GzmA-i...
Granzyme A (GzmA) is considered a major proapoptotic protease. We have discovered that GzmA-induced ...
Cytotoxic lymphocytes rapidly respond and destroy both malignant cells and cells infected with intra...
In this issue of Immunity, Devadas and colleagues (2006) reveal that granzyme B, long known as a med...
In this issue of Immunity, Metkar et al. (2008) present evidence that granzyme A plays a role in inf...
The cytotoxic properties of granzymes are well established, though recent publications suggest addit...
Granzymes are a family of serine proteases stored in granules inside cytotoxic cells of the immune s...
Granzymes (Grs) are serine proteases mainly produced by cytotoxic lymphocytes and are traditionally ...
Granzyme A: cell death–inducing protease, proinflammatory agent, or both? We recently showed that gr...
It has been well established that granzymes released by cytotoxic lymphocytes induce cell death in v...
Cytotoxic lymphocytes are the key effector immune cells that deal with tumor cells and virus-infecte...
THESIS 9588Excerpt from introduction: In all vertebrate organisms a properly functioning immune syst...
Lymphocyte perforin and serine protease granzymes are well-recognized extrinsic mediators of apoptos...
Inflammation is strictly interconnected to anti-inflammatory mechanisms to maintain tissue homeostas...
The cytotoxic cell granule secretory pathway is viewed as indispensable for eliminating tumor and vi...
SummaryGranzyme A (GzmA) is considered a major proapoptotic protease. We have discovered that GzmA-i...
Granzyme A (GzmA) is considered a major proapoptotic protease. We have discovered that GzmA-induced ...
Cytotoxic lymphocytes rapidly respond and destroy both malignant cells and cells infected with intra...
In this issue of Immunity, Devadas and colleagues (2006) reveal that granzyme B, long known as a med...
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