Cell death needs to be detected by immune cells. In this issue of Immunity, Ahrens et al. (2012) and Zhang et al. (2012) show that actin filaments become exposed on necrotic cells and act as ligands for the C-type lectin receptor Clec9a
C type lectins recognize pathogens by binding to pathogen-specific carbohydrate residues. The findin...
Sensing tissue damage is an ancient function of immune cells that is central to the regulation of in...
Engagement of the T cell receptor leads to the accumulation of filamentous actin, which is necessary...
Contains fulltext : 81008.pdf (publisher's version ) (Closed access)Recent studies...
SummaryRecent studies have shown that C-type lectins, a family of surface receptors known to recogni...
International audienceC-type lectin-like receptors (CLRs) represent a family of transmembrane patter...
SummaryThe immune system must distinguish viable cells from cells damaged by physical and infective ...
The immune system must distinguish viable cells from cells damaged by physical and infective process...
Cell death needs to be detected by immune cells. In this issue of Immunity, Ahrens et al. (2012) and...
The immune system must distinguish viable cells from cells damaged by physical and infective process...
SummaryDNGR-1 is a C-type lectin receptor that binds F-actin exposed by dying cells and facilitates ...
After both sterile and infectious insults, damage is inflicted on tissues leading to accidental or p...
Dendritic cells (DC) are present in essentially every tissue, where they operate at the interface of...
Summary: Conventional type 1 DCs (cDC1s) excel at cross-presentation of dead cell-associated antigen...
The galectin family of lectins regulates multiple biologic functions, such as development, inflammat...
C type lectins recognize pathogens by binding to pathogen-specific carbohydrate residues. The findin...
Sensing tissue damage is an ancient function of immune cells that is central to the regulation of in...
Engagement of the T cell receptor leads to the accumulation of filamentous actin, which is necessary...
Contains fulltext : 81008.pdf (publisher's version ) (Closed access)Recent studies...
SummaryRecent studies have shown that C-type lectins, a family of surface receptors known to recogni...
International audienceC-type lectin-like receptors (CLRs) represent a family of transmembrane patter...
SummaryThe immune system must distinguish viable cells from cells damaged by physical and infective ...
The immune system must distinguish viable cells from cells damaged by physical and infective process...
Cell death needs to be detected by immune cells. In this issue of Immunity, Ahrens et al. (2012) and...
The immune system must distinguish viable cells from cells damaged by physical and infective process...
SummaryDNGR-1 is a C-type lectin receptor that binds F-actin exposed by dying cells and facilitates ...
After both sterile and infectious insults, damage is inflicted on tissues leading to accidental or p...
Dendritic cells (DC) are present in essentially every tissue, where they operate at the interface of...
Summary: Conventional type 1 DCs (cDC1s) excel at cross-presentation of dead cell-associated antigen...
The galectin family of lectins regulates multiple biologic functions, such as development, inflammat...
C type lectins recognize pathogens by binding to pathogen-specific carbohydrate residues. The findin...
Sensing tissue damage is an ancient function of immune cells that is central to the regulation of in...
Engagement of the T cell receptor leads to the accumulation of filamentous actin, which is necessary...