AbstractBy a highly sensitive enzyme immunoassay we measured the level of nerve growth factor (NGF) in the cerebellum and cerebrum of the neurologically mutant mice, weaver, reeler and Purkinje cell degeneration (PCD). A significant decrease in NGF level was observed in both cerebellum and cerebrum of weaver and reeler mutants of either sex. However, there was no such difference between normals and mutants in the case of the PCD mice. These results show that weaver and reeler mice have abnormalities of NGF synthesis and/or degradation not only in the cerebellum but also in the cerebrum
Ts65Dn mice are a genetic model for Down syndrome. Among others, these mice have cerebellar patholog...
AbstractThe weaver mouse mutation is a genetic defect of unknown origin that leads to impairment of ...
Niemann-Pick type C1 disease (NPCD) is a lysosomal storage disorder due to mutations in NPC1, a lyso...
AbstractBy a highly sensitive enzyme immunoassay we measured the level of nerve growth factor (NGF) ...
The pattern of BDNF and neurotrophin-3 (NT-3) gene expression was analyzed in the cerebellum of wild...
The Purkinje target cells for noradrenergic fibers originating in the locus coeruleus are considered...
We previously showed that anti-nerve growth factor (NGF) antibodies expressed in transgenic mice (AD...
Neurodegenerative disorders (NDD) are an ever-increasing burden on healthcare; consequently, elucida...
The disruption of the nerve growth factor (NGF) gene in transgenic mice leads to a lethal phenotype ...
The disruption of the nerve growth factor (NGF) gene in transgenic mice leads to a lethal phenotype ...
The architectonic and hodologic organization of the reeler cerebellum has been studied by means of i...
EXPERIMENTAL STUDY OF MECHANISMS OF NEURODEGENERATION IN DIFFERENT CONDITIONS - SUMMARY MUDr. Zdeňka...
The molecular mechanism of environmental enrichment (EE) on brain function and anatomy has been part...
Neurofibromatosis type 1 (NF1) is an autosomal dominantly inherited disease, characterized by variou...
Analysis of the molecular basis of neuronal migration in the mammalian CNS relies critically on the ...
Ts65Dn mice are a genetic model for Down syndrome. Among others, these mice have cerebellar patholog...
AbstractThe weaver mouse mutation is a genetic defect of unknown origin that leads to impairment of ...
Niemann-Pick type C1 disease (NPCD) is a lysosomal storage disorder due to mutations in NPC1, a lyso...
AbstractBy a highly sensitive enzyme immunoassay we measured the level of nerve growth factor (NGF) ...
The pattern of BDNF and neurotrophin-3 (NT-3) gene expression was analyzed in the cerebellum of wild...
The Purkinje target cells for noradrenergic fibers originating in the locus coeruleus are considered...
We previously showed that anti-nerve growth factor (NGF) antibodies expressed in transgenic mice (AD...
Neurodegenerative disorders (NDD) are an ever-increasing burden on healthcare; consequently, elucida...
The disruption of the nerve growth factor (NGF) gene in transgenic mice leads to a lethal phenotype ...
The disruption of the nerve growth factor (NGF) gene in transgenic mice leads to a lethal phenotype ...
The architectonic and hodologic organization of the reeler cerebellum has been studied by means of i...
EXPERIMENTAL STUDY OF MECHANISMS OF NEURODEGENERATION IN DIFFERENT CONDITIONS - SUMMARY MUDr. Zdeňka...
The molecular mechanism of environmental enrichment (EE) on brain function and anatomy has been part...
Neurofibromatosis type 1 (NF1) is an autosomal dominantly inherited disease, characterized by variou...
Analysis of the molecular basis of neuronal migration in the mammalian CNS relies critically on the ...
Ts65Dn mice are a genetic model for Down syndrome. Among others, these mice have cerebellar patholog...
AbstractThe weaver mouse mutation is a genetic defect of unknown origin that leads to impairment of ...
Niemann-Pick type C1 disease (NPCD) is a lysosomal storage disorder due to mutations in NPC1, a lyso...