In this issue of Immunity, Liu et al. (2007) show that V(D)J recombinase binds chromatin marked by H3K4 trimethylation. Because this mark associates with active promoters, the finding forges a new link between transcription, epigenetics, and recombinase targeting during lymphocyte development
International audienceV(D)J recombination assembles antigen-specific immunoglobulin and T-cell recep...
V(D)J recombination is essential for the generation of diverse antigen receptor (AgR) repertoires. I...
International audienceV(D)J recombination assembles antigen receptor genes from germline V, D and J ...
In this issue of Immunity, Liu et al. (2007) show that V(D)J recombinase binds chromatin marked by H...
V(D)J recombination of antigen receptor gene segments in B and T cells is mediated by the lymphoid-s...
International audienceChromosome breaks are dangerous business, carrying the risk of loss of genetic...
AbstractV(D)J recombination is of fundamental importance to the generation of diverse antigen recept...
V(D)J recombination is the process that generates the primary antigen receptor repertoire of the ada...
V(D)J recombination assembles Ag receptor genes during lymphocyte development. Enhancers at AR loci ...
V(D)J recombination substrate choice is regulated to ensure that the appropriate gene segments are r...
SummaryV(D)J recombination is initiated by the recombination activating gene (RAG) proteins RAG-1 an...
Expression of V(D)J recombinase activity in developing lymphocytes is absolutely required for initia...
A large number of lymphoid malignancies is characterized by specific chromosomal translocations, whi...
AbstractThe role of the germline transcriptional promoter, PDβ1, in V(D)J recombination at the T cel...
V(D)J recombination is essential for the generation of diverse antigen receptor (AgR) repertoires. I...
International audienceV(D)J recombination assembles antigen-specific immunoglobulin and T-cell recep...
V(D)J recombination is essential for the generation of diverse antigen receptor (AgR) repertoires. I...
International audienceV(D)J recombination assembles antigen receptor genes from germline V, D and J ...
In this issue of Immunity, Liu et al. (2007) show that V(D)J recombinase binds chromatin marked by H...
V(D)J recombination of antigen receptor gene segments in B and T cells is mediated by the lymphoid-s...
International audienceChromosome breaks are dangerous business, carrying the risk of loss of genetic...
AbstractV(D)J recombination is of fundamental importance to the generation of diverse antigen recept...
V(D)J recombination is the process that generates the primary antigen receptor repertoire of the ada...
V(D)J recombination assembles Ag receptor genes during lymphocyte development. Enhancers at AR loci ...
V(D)J recombination substrate choice is regulated to ensure that the appropriate gene segments are r...
SummaryV(D)J recombination is initiated by the recombination activating gene (RAG) proteins RAG-1 an...
Expression of V(D)J recombinase activity in developing lymphocytes is absolutely required for initia...
A large number of lymphoid malignancies is characterized by specific chromosomal translocations, whi...
AbstractThe role of the germline transcriptional promoter, PDβ1, in V(D)J recombination at the T cel...
V(D)J recombination is essential for the generation of diverse antigen receptor (AgR) repertoires. I...
International audienceV(D)J recombination assembles antigen-specific immunoglobulin and T-cell recep...
V(D)J recombination is essential for the generation of diverse antigen receptor (AgR) repertoires. I...
International audienceV(D)J recombination assembles antigen receptor genes from germline V, D and J ...
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