Age-related mitochondrial dysfunction is thought to contribute to mammalian aging, particularly in postmitotic tissues that rely heavily on oxidative phosphorylation. A new study (Gomes et al., 2013) shows that reduced levels of nicotinamide adenine dinucleotide (NAD+) contribute to the mitochondrial decay associated with skeletal muscle aging and that sirtuin 1 (SIRT1) modulates this process
Adult stem cells (SCs) are essential for tissue maintenance and regeneration yet are susceptible to ...
The quality of mitochondria is a key determinant of mitochondrial ATP production and reactive oxygen...
SummaryMitochondrial dysfunction is strongly associated with aging. A recent study shows that reduce...
Age-related mitochondrial dysfunction is thought to contribute to mammalian aging, particularly in p...
Oxidative stress and decreased DNA damage repair in vertebrates increase with age also due to lowere...
Nicotinamide adenine dinucleotide (NAD[superscript +]) is a classical coenzyme mediating many redox ...
The cofactor nicotinamide adenine dinucleotide (NAD+) has emerged as a key regulator of metabolism, ...
The cofactor nicotinamide adenine dinucleotide (NAD+) has emerged as a key regulator of metabolism, ...
The progressive decline of muscle mass and function called sarcopenia is a multi-factorial process a...
Nicotinamide adenine dinucleotide (NAD+) is a vital coenzyme in redox reactions. NAD+ is also import...
AB The coenzyme NAD+ is critical in cellular bioenergetics and adaptive stress responses. Its deplet...
Mammalian skeletal muscle is a highly dynamic organ capable of structural and metabolic remodeling i...
Discovered in the beginning of the 20(th) century, nicotinamide adenine dinucleotide (NAD(+)) has ev...
Mammalian skeletal muscle is a highly dynamic organ capable of structural and metabolic remodeling i...
Diseases due to DNA damage repair machinery defects can resemble premature aging. In this issue of C...
Adult stem cells (SCs) are essential for tissue maintenance and regeneration yet are susceptible to ...
The quality of mitochondria is a key determinant of mitochondrial ATP production and reactive oxygen...
SummaryMitochondrial dysfunction is strongly associated with aging. A recent study shows that reduce...
Age-related mitochondrial dysfunction is thought to contribute to mammalian aging, particularly in p...
Oxidative stress and decreased DNA damage repair in vertebrates increase with age also due to lowere...
Nicotinamide adenine dinucleotide (NAD[superscript +]) is a classical coenzyme mediating many redox ...
The cofactor nicotinamide adenine dinucleotide (NAD+) has emerged as a key regulator of metabolism, ...
The cofactor nicotinamide adenine dinucleotide (NAD+) has emerged as a key regulator of metabolism, ...
The progressive decline of muscle mass and function called sarcopenia is a multi-factorial process a...
Nicotinamide adenine dinucleotide (NAD+) is a vital coenzyme in redox reactions. NAD+ is also import...
AB The coenzyme NAD+ is critical in cellular bioenergetics and adaptive stress responses. Its deplet...
Mammalian skeletal muscle is a highly dynamic organ capable of structural and metabolic remodeling i...
Discovered in the beginning of the 20(th) century, nicotinamide adenine dinucleotide (NAD(+)) has ev...
Mammalian skeletal muscle is a highly dynamic organ capable of structural and metabolic remodeling i...
Diseases due to DNA damage repair machinery defects can resemble premature aging. In this issue of C...
Adult stem cells (SCs) are essential for tissue maintenance and regeneration yet are susceptible to ...
The quality of mitochondria is a key determinant of mitochondrial ATP production and reactive oxygen...
SummaryMitochondrial dysfunction is strongly associated with aging. A recent study shows that reduce...
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