AbstractVarious studies have suggested that the rate of adult skin healing may be in some way dependent on signals emanating from cutaneous nerves. Further, it appears that adult wounds become hyperinnervated by sensory nerves during the process of healing. In order to investigate this reciprocal relationship further, we have used a simple embryonic model to look at the effect of wounds on nerves, and conversely, the effect of nerves on wounds. We find that wounds made to the dorsum of the chick wing bud, at a stage prior to normal innervation (at E4), or soon after the normal establishment of cutaneous innervation (at E7), subtly alter the pattern of branching by perturbing developmental guidance cues, but do not cause hyperinnervation, wh...
Wound closure in the ectoderm of Xenopus early neurulae and chick primitive-streak embryos has been ...
We review the mounting evidence that regeneration is induced in wounds in skin and peripheral nerves...
AbstractIt is now well documented that motoneurons are specified to innervate particular target musc...
Using a chick embryo model I have investigated three related problems in patterning of cutaneous ner...
Peripheral nerves travel to their targets along precise routes, and it is likely that different cues...
AbstractIn some developing systems, growing axons are attracted to their target site by a diffusible...
If the somitic mesoderm of a 2-day chick embryo is destroyed by X-irradiation, the adjacent limb dev...
Wound healing in the embryo, just as in the adult, comprises two tissue movements: re-epithelialisat...
Motoneurones that supply the vertebrate limb innervate their muscle targets in a highly reproducible...
AbstractOur previous surgical manipulations have shown that the target ectoderm is necessary for the...
International audienceThe skin is a highly sensitive organ. It is densely innervated with different ...
AbstractTarget tissues are thought to provide important cues for growing axons, yet there is little ...
AbstractDuring development, motor and sensory axons grow to peripheral targets with remarkable preci...
This study was carried out in order to determine what factors control the differentiation of certain...
Chick embryonic corneal wounds display a remarkable capacity to fully and rapidly regenerate. Wherea...
Wound closure in the ectoderm of Xenopus early neurulae and chick primitive-streak embryos has been ...
We review the mounting evidence that regeneration is induced in wounds in skin and peripheral nerves...
AbstractIt is now well documented that motoneurons are specified to innervate particular target musc...
Using a chick embryo model I have investigated three related problems in patterning of cutaneous ner...
Peripheral nerves travel to their targets along precise routes, and it is likely that different cues...
AbstractIn some developing systems, growing axons are attracted to their target site by a diffusible...
If the somitic mesoderm of a 2-day chick embryo is destroyed by X-irradiation, the adjacent limb dev...
Wound healing in the embryo, just as in the adult, comprises two tissue movements: re-epithelialisat...
Motoneurones that supply the vertebrate limb innervate their muscle targets in a highly reproducible...
AbstractOur previous surgical manipulations have shown that the target ectoderm is necessary for the...
International audienceThe skin is a highly sensitive organ. It is densely innervated with different ...
AbstractTarget tissues are thought to provide important cues for growing axons, yet there is little ...
AbstractDuring development, motor and sensory axons grow to peripheral targets with remarkable preci...
This study was carried out in order to determine what factors control the differentiation of certain...
Chick embryonic corneal wounds display a remarkable capacity to fully and rapidly regenerate. Wherea...
Wound closure in the ectoderm of Xenopus early neurulae and chick primitive-streak embryos has been ...
We review the mounting evidence that regeneration is induced in wounds in skin and peripheral nerves...
AbstractIt is now well documented that motoneurons are specified to innervate particular target musc...