A new report (Szutorisz et al., 2006) suggests that embryonic stem (ES) cells adopt an unusual strategy to remain perpetually poised for differentiation. Apparently, ES cells use the proteasome to target transcriptional preinitiation complexes, thus minimizing transcriptional noise at genes that promote differentiation
During recent years, increased efforts have focused on elucidating the pluripotency and self-renewal...
Human embryonic stem cells (hESCs) exhibit high levels of proteasome activity, an intrinsic characte...
SummaryHuman embryonic stem (hES) cells show an atypical cell-cycle regulation characterized by a hi...
A new report (Szutorisz et al., 2006) suggests that embryonic stem (ES) cells adopt an unusual strat...
SummaryThe ability of stem cells to activate different gene expression programs requires the choreog...
The molecular mechanisms underlying pluripotency and lineage specification from embryonic stem cells...
SummaryThe molecular mechanisms underlying pluripotency and lineage specification from embryonic ste...
SummaryStem cells occupy variable environments where they must distinguish stochastic fluctuations f...
SummaryCell fate decisions are fundamental for development, but we do not know how transcriptional n...
Systems biology studies have revealed transcriptional networks and proteomic signatures critical for...
During the past decade Embryonic Stem cells (ESCs) became particularly attractive for translational...
Gene expression analyses of embryonic stem cells (ESCs) will help to uncover or further define signa...
There is evidence that pluripotency of mouse embryonic stem (ES) cells is associated with the activi...
In embryonic stem cells (ESCs), silent genes with major developmental functions display a unique epi...
Embryonic stem cells (ESCs) are pluripotent cells able to grow indefinitely in culture and to differ...
During recent years, increased efforts have focused on elucidating the pluripotency and self-renewal...
Human embryonic stem cells (hESCs) exhibit high levels of proteasome activity, an intrinsic characte...
SummaryHuman embryonic stem (hES) cells show an atypical cell-cycle regulation characterized by a hi...
A new report (Szutorisz et al., 2006) suggests that embryonic stem (ES) cells adopt an unusual strat...
SummaryThe ability of stem cells to activate different gene expression programs requires the choreog...
The molecular mechanisms underlying pluripotency and lineage specification from embryonic stem cells...
SummaryThe molecular mechanisms underlying pluripotency and lineage specification from embryonic ste...
SummaryStem cells occupy variable environments where they must distinguish stochastic fluctuations f...
SummaryCell fate decisions are fundamental for development, but we do not know how transcriptional n...
Systems biology studies have revealed transcriptional networks and proteomic signatures critical for...
During the past decade Embryonic Stem cells (ESCs) became particularly attractive for translational...
Gene expression analyses of embryonic stem cells (ESCs) will help to uncover or further define signa...
There is evidence that pluripotency of mouse embryonic stem (ES) cells is associated with the activi...
In embryonic stem cells (ESCs), silent genes with major developmental functions display a unique epi...
Embryonic stem cells (ESCs) are pluripotent cells able to grow indefinitely in culture and to differ...
During recent years, increased efforts have focused on elucidating the pluripotency and self-renewal...
Human embryonic stem cells (hESCs) exhibit high levels of proteasome activity, an intrinsic characte...
SummaryHuman embryonic stem (hES) cells show an atypical cell-cycle regulation characterized by a hi...