AbstractFibrillogenesis is a major feature of Alzheimer's disease (AD) and other neurodegenerative diseases. Fibers are correlated with disease severity and they have been implicated as playing a direct role in disease pathophysiology. In studies of tau, instead of finding causality with tau fibrils, we found that tau is associated with reduction of oxidative stress. Biochemical findings show that tau oxidative modifications are regulated by phosphorylation and that tau found in neurofibrillary tangles is oxidatively modified, suggesting that tau is closely linked to the biology, not toxicity, of AD
The microtubule-associated protein tau is integral to the pathogenesis of Alzheimer's disease (AD), ...
The three major lesions observed within Alzheimer\u27s disease (AD) brain are senile plaques (SPs), ...
Alzheimer's disease (AD) and related dementias constitute a major public health issue due to an incr...
AbstractFibrillogenesis is a major feature of Alzheimer's disease (AD) and other neurodegenerative d...
Robinson, Anne SkajaTauopathies are a class of neurodegenerative diseases consisting of the aggregat...
Fibrillar deposits of highly phosphorylated tau are a key pathological feature of several neurodegen...
Many hypotheses have been raised regarding the pathophysiology of Alzheimer’s disease (AD). Because ...
Many hypotheses have been raised regarding the pathophysiology of Alzheimer's disease (AD). Because ...
Tau, one of the major microtubule-associated proteins, modulates the dynamic properties of microtubu...
Alzheimer’s disease (AD) is the leading cause of dementia in elderly people. Amyloid beta (Aβ) depos...
Alzheimer’s disease (AD) is defined by the concurrence of abnormal aggregates composed of phosphoryl...
Pathological tau protein aggregates can be found in brain of patients with some of the neurodegenera...
Researchers familiar with Alzheimer’s Disease (AD) refer to two common pathological hallmarks: β-amy...
Alzheimer’s disease (AD) is the most common form of dementia. The pathological hallmarks of AD are a...
One of the defining pathological features of Alzheimer disease (AD) is the intraneuronal accumulatio...
The microtubule-associated protein tau is integral to the pathogenesis of Alzheimer's disease (AD), ...
The three major lesions observed within Alzheimer\u27s disease (AD) brain are senile plaques (SPs), ...
Alzheimer's disease (AD) and related dementias constitute a major public health issue due to an incr...
AbstractFibrillogenesis is a major feature of Alzheimer's disease (AD) and other neurodegenerative d...
Robinson, Anne SkajaTauopathies are a class of neurodegenerative diseases consisting of the aggregat...
Fibrillar deposits of highly phosphorylated tau are a key pathological feature of several neurodegen...
Many hypotheses have been raised regarding the pathophysiology of Alzheimer’s disease (AD). Because ...
Many hypotheses have been raised regarding the pathophysiology of Alzheimer's disease (AD). Because ...
Tau, one of the major microtubule-associated proteins, modulates the dynamic properties of microtubu...
Alzheimer’s disease (AD) is the leading cause of dementia in elderly people. Amyloid beta (Aβ) depos...
Alzheimer’s disease (AD) is defined by the concurrence of abnormal aggregates composed of phosphoryl...
Pathological tau protein aggregates can be found in brain of patients with some of the neurodegenera...
Researchers familiar with Alzheimer’s Disease (AD) refer to two common pathological hallmarks: β-amy...
Alzheimer’s disease (AD) is the most common form of dementia. The pathological hallmarks of AD are a...
One of the defining pathological features of Alzheimer disease (AD) is the intraneuronal accumulatio...
The microtubule-associated protein tau is integral to the pathogenesis of Alzheimer's disease (AD), ...
The three major lesions observed within Alzheimer\u27s disease (AD) brain are senile plaques (SPs), ...
Alzheimer's disease (AD) and related dementias constitute a major public health issue due to an incr...