AbstractThe mechanical properties of cells and tissues play a well-known role in physiology and disease. The model organism Caenorhabditis elegans exhibits mechanical properties that are still poorly understood, but are thought to be dominated by its collagen-rich outer cuticle. We use a microfluidic technique to reveal that the worm responds linearly to low applied hydrostatic stress, exhibiting a volumetric compression with a bulk modulus, κ = 140 ± 20 kPa; applying negative pressures leads to volumetric expansion of the worm, with a similar bulk modulus. Surprisingly, however, we find that a variety of collagen mutants and pharmacological perturbations targeting the cuticle do not impact the bulk modulus. Moreover, the worm exhibits dram...
AbstractWith a simple and versatile microcantilever-based force measurement technique, we have probe...
Many cell movements proceed via a crawling mechanism, where polymerization of the cytoskeletal prote...
International audienceThe purpose of this work is to provide a biomechanical model to investigate th...
AbstractThe mechanical properties of cells and tissues play a well-known role in physiology and dise...
AbstractBody mechanics in the nematode Caenorhabditis elegans are central to both mechanosensation a...
Caenorhabditis elegans (C. elegans) is one of the most studied organisms by biologists. Composed of ...
Cutaneous mechanosensory neurons are activated by mechanical loads applied to the skin, and these st...
International audienceThe morphogenesis of tissues, like the deformation of an object, results from ...
International audienceThe role of the actomyosin network is investigated in the elongation of C. ele...
The viscoelastic material properties of the model organism C. elegans were probed with a micropipett...
We characterize the lengthscale-dependent rheological properties of mucus from the ubiquitous Chaeto...
AbstractHow do animal tissues resist the shearing forces to which they are exposed during locomotion...
The C. elegans hypodermis is a single epithelial cell layer separated from the musculature by a thin...
Understanding how cells respond to and remodel their extracellular environment is foundational to mo...
In the study of the molecular origins of behaviour, the nematode Caenorhabditis elegans has emerged ...
AbstractWith a simple and versatile microcantilever-based force measurement technique, we have probe...
Many cell movements proceed via a crawling mechanism, where polymerization of the cytoskeletal prote...
International audienceThe purpose of this work is to provide a biomechanical model to investigate th...
AbstractThe mechanical properties of cells and tissues play a well-known role in physiology and dise...
AbstractBody mechanics in the nematode Caenorhabditis elegans are central to both mechanosensation a...
Caenorhabditis elegans (C. elegans) is one of the most studied organisms by biologists. Composed of ...
Cutaneous mechanosensory neurons are activated by mechanical loads applied to the skin, and these st...
International audienceThe morphogenesis of tissues, like the deformation of an object, results from ...
International audienceThe role of the actomyosin network is investigated in the elongation of C. ele...
The viscoelastic material properties of the model organism C. elegans were probed with a micropipett...
We characterize the lengthscale-dependent rheological properties of mucus from the ubiquitous Chaeto...
AbstractHow do animal tissues resist the shearing forces to which they are exposed during locomotion...
The C. elegans hypodermis is a single epithelial cell layer separated from the musculature by a thin...
Understanding how cells respond to and remodel their extracellular environment is foundational to mo...
In the study of the molecular origins of behaviour, the nematode Caenorhabditis elegans has emerged ...
AbstractWith a simple and versatile microcantilever-based force measurement technique, we have probe...
Many cell movements proceed via a crawling mechanism, where polymerization of the cytoskeletal prote...
International audienceThe purpose of this work is to provide a biomechanical model to investigate th...