Fifty-five primary and 33 metastatic surgically removed melanoma lesions were stained in indirect immunoperoxidase with anti HLA-DR, DQ, and DP monoclonal antibodies and with the monoclonal antibody CL203.4 to a 96-K melanoma associated antigen (MAA). The latter antigen may represent a marker to monitor susceptibility of melanoma cells to modulation by IFN-γ, because it is highly susceptible to induction by IFN-γ-. In primary melanomas 44%, 29%, 10%, and 55% of the lesions tested were evidently stained by anti HLA-DR, DQ, DP, and 96-K MAA monoclonal antibodies, respectively. A statistically significant association (P < 0.01) was demonstrated between the degree of intratumoral lymphocytic infiltrate and the expression of HLA-DR and HLA-DQ an...
The role of human leukocyte antigens (HLA) class II molecules in transducing intracellular signals i...
Advanced steps of tumor progression are generally characterized by an increased growth fraction with...
Background: The human leukocyte antigen (HLA) class II molecules are constitutively expressed in som...
Fifty-five primary and 33 metastatic surgically removed melanoma lesions were stained in indirect im...
Human melanoma cells freshly isolated from 20 patients with primary and 73 patients with metastatic ...
Ninety-three primary malignant melanomas of the skin were typed immunohistologically for the express...
The expression of class I and class II HLA antigens has been studied on primary and metastatic human...
Expression of HLA class I molecules is essential for the recognition of tumor cells by CD8+ T cells....
Evidence for heterogeneity of several biological features of human malignant melanoma (Me) like morp...
Conflicting evidences suggested that levels of HLA-A and -B antigens expressed on normal and neoplas...
Six monoclonal antibodies(Mabs) including 4 anti-melanoma, one anti-glioma, and one anti-HLA-DR have...
Human leukocyte antigen (HLA) class II molecules are polymorphic cell surface glycoproteins that are...
The role of human leukocyte antigens (HLA) class II molecules in transducing intracellular signals i...
Using monoclonal antibodies, recombinant human γ-interferon, and fluorescence-activated cell sorter,...
Lymphocytes from melanoma patients were stimulated in mixed culture with autologous tumor cells (MLT...
The role of human leukocyte antigens (HLA) class II molecules in transducing intracellular signals i...
Advanced steps of tumor progression are generally characterized by an increased growth fraction with...
Background: The human leukocyte antigen (HLA) class II molecules are constitutively expressed in som...
Fifty-five primary and 33 metastatic surgically removed melanoma lesions were stained in indirect im...
Human melanoma cells freshly isolated from 20 patients with primary and 73 patients with metastatic ...
Ninety-three primary malignant melanomas of the skin were typed immunohistologically for the express...
The expression of class I and class II HLA antigens has been studied on primary and metastatic human...
Expression of HLA class I molecules is essential for the recognition of tumor cells by CD8+ T cells....
Evidence for heterogeneity of several biological features of human malignant melanoma (Me) like morp...
Conflicting evidences suggested that levels of HLA-A and -B antigens expressed on normal and neoplas...
Six monoclonal antibodies(Mabs) including 4 anti-melanoma, one anti-glioma, and one anti-HLA-DR have...
Human leukocyte antigen (HLA) class II molecules are polymorphic cell surface glycoproteins that are...
The role of human leukocyte antigens (HLA) class II molecules in transducing intracellular signals i...
Using monoclonal antibodies, recombinant human γ-interferon, and fluorescence-activated cell sorter,...
Lymphocytes from melanoma patients were stimulated in mixed culture with autologous tumor cells (MLT...
The role of human leukocyte antigens (HLA) class II molecules in transducing intracellular signals i...
Advanced steps of tumor progression are generally characterized by an increased growth fraction with...
Background: The human leukocyte antigen (HLA) class II molecules are constitutively expressed in som...