It is well established that canonical Wnt signaling in bone regulates bone mass. Much less is known about the role of noncanonical Wnt signaling. Maeda and colleagues now report in Nature Medicine that Wnt5a-Ror2 crosstalk between bone cells enhances bone resorption, thereby negatively regulating skeletal homeostasis (Maeda et al., 2012)
The Wnt pathway is involved in several processes essential for bone development and homeostasis. For...
Mesenchymal stem cells (MSCs) are multipotent cells that can be differentiated into osteoblasts and ...
Multiple myeloma (MM) is characterized by the impaired osteogenic differentiation of human mesenchym...
It is well established that canonical Wnt signaling in bone regulates bone mass. Much less is known ...
The Wnt signalling pathway is one of the central signalling pathways in bone development, homeostasi...
The Wnt signalling pathway is one of the central signalling pathways in bone development, homeostasi...
SummaryWnt proteins (Wnts) are palmitoylated and glycosylated ligands that play a central role in th...
Wnt signalling has an essential role in regulating bone formation and remodelling during embryonic d...
The skeleton as an organ is widely distributed throughout the entire vertebrate body. Wnt signaling ...
Abstract. Wnt signaling is involved not only in embryonic development but also in maintenance of hom...
The Wnt and the bone morphogenic protein (BMP) pathways are evolutionarily conserved and essentially...
Fracture repair is a complex regenerative process initiated in response to injury, resulting in opti...
Reports implicating Wnt signalling in the regulation of bone mass have prompted widespread interest ...
The past decade has seen significant advances in our understanding of skeletal homeostasis and the m...
This thesis relates to some new aspects on the regulation of bone healing. In the last few years, Wn...
The Wnt pathway is involved in several processes essential for bone development and homeostasis. For...
Mesenchymal stem cells (MSCs) are multipotent cells that can be differentiated into osteoblasts and ...
Multiple myeloma (MM) is characterized by the impaired osteogenic differentiation of human mesenchym...
It is well established that canonical Wnt signaling in bone regulates bone mass. Much less is known ...
The Wnt signalling pathway is one of the central signalling pathways in bone development, homeostasi...
The Wnt signalling pathway is one of the central signalling pathways in bone development, homeostasi...
SummaryWnt proteins (Wnts) are palmitoylated and glycosylated ligands that play a central role in th...
Wnt signalling has an essential role in regulating bone formation and remodelling during embryonic d...
The skeleton as an organ is widely distributed throughout the entire vertebrate body. Wnt signaling ...
Abstract. Wnt signaling is involved not only in embryonic development but also in maintenance of hom...
The Wnt and the bone morphogenic protein (BMP) pathways are evolutionarily conserved and essentially...
Fracture repair is a complex regenerative process initiated in response to injury, resulting in opti...
Reports implicating Wnt signalling in the regulation of bone mass have prompted widespread interest ...
The past decade has seen significant advances in our understanding of skeletal homeostasis and the m...
This thesis relates to some new aspects on the regulation of bone healing. In the last few years, Wn...
The Wnt pathway is involved in several processes essential for bone development and homeostasis. For...
Mesenchymal stem cells (MSCs) are multipotent cells that can be differentiated into osteoblasts and ...
Multiple myeloma (MM) is characterized by the impaired osteogenic differentiation of human mesenchym...