The Notch pathway is an attractive therapeutic target for treatment of cancer and T cell-mediated pathology, but Notch inhibition leads to many side effects. Pinnell et al. (2015) demonstrate that oncogenic functions can be separated biochemically from other functions of Notch, opening new options for more selective targeting of this pathway
Notch signalling is a conserved developmental pathway involved, inter alia, in cell-fate decision, m...
AbstractThe Notch pathway is involved in cell proliferation, differentiation and survival. The Notch...
Abstract Notch signaling is a highly conserved pathway in all metazoans, which is deeply involved in...
The Notch pathway is an attractive therapeutic target for treatment of cancer and T cell-mediated pa...
Accumulating preclinical and clinical evidence supports a pro-oncogenic function for Notch signaling...
Notch signaling is a highly conserved pathway in all metazoans, which is deeply involved in the regu...
Notch signaling is a highly conserved pathway in all metazoans, which is deeply involved in the regu...
Notch signaling is a highly conserved pathway in all metazoans, which is deeply involved in the regu...
AbstractThe Notch pathway is known for its multiple important roles in development and tissue homeos...
Notch signaling is a highly conserved pathway in all metazoans, which is deeply involved in the regu...
Background: Notch is a multifaceted protein that plays a fundamental role in fetal development and t...
Notch signaling guides cell fate decisions by affecting proliferation, apoptosis, stem cell self-ren...
Notch signaling controls cell fate decisions including during development and stem cell renewal and ...
The highly conserved Notch signaling pathway plays pleiotropic roles during embryonic development an...
The highly conserved Notch signaling pathway plays pleiotropic roles during embryonic development an...
Notch signalling is a conserved developmental pathway involved, inter alia, in cell-fate decision, m...
AbstractThe Notch pathway is involved in cell proliferation, differentiation and survival. The Notch...
Abstract Notch signaling is a highly conserved pathway in all metazoans, which is deeply involved in...
The Notch pathway is an attractive therapeutic target for treatment of cancer and T cell-mediated pa...
Accumulating preclinical and clinical evidence supports a pro-oncogenic function for Notch signaling...
Notch signaling is a highly conserved pathway in all metazoans, which is deeply involved in the regu...
Notch signaling is a highly conserved pathway in all metazoans, which is deeply involved in the regu...
Notch signaling is a highly conserved pathway in all metazoans, which is deeply involved in the regu...
AbstractThe Notch pathway is known for its multiple important roles in development and tissue homeos...
Notch signaling is a highly conserved pathway in all metazoans, which is deeply involved in the regu...
Background: Notch is a multifaceted protein that plays a fundamental role in fetal development and t...
Notch signaling guides cell fate decisions by affecting proliferation, apoptosis, stem cell self-ren...
Notch signaling controls cell fate decisions including during development and stem cell renewal and ...
The highly conserved Notch signaling pathway plays pleiotropic roles during embryonic development an...
The highly conserved Notch signaling pathway plays pleiotropic roles during embryonic development an...
Notch signalling is a conserved developmental pathway involved, inter alia, in cell-fate decision, m...
AbstractThe Notch pathway is involved in cell proliferation, differentiation and survival. The Notch...
Abstract Notch signaling is a highly conserved pathway in all metazoans, which is deeply involved in...
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