AbstractIn the present study, we used bone marrow transplanted mice and revealed the role of bone marrow derived cells in liver regeneration after partial hepatectomy (PH). Irradiated wild type (WT) mice received a bone marrow transplant from either WT, TNF (tumor necrosis factor)-α knockout (KO), or interleukin (IL)-6 KO donors. Both TNF-α KO- and IL-6 KO-transplanted mice compared with WT-transplanted mice showed decreased hepatocyte DNA synthesis after PH. TNF-α KO-transplanted mice showed no nuclear factor kappa B (NF-κB) and signal transducer and activator of transcription (STAT) 3 binding after PH, while IL-6 KO-transplanted mice showed NF-κB, but not STAT3, binding. Lack of AP-1 or C/EBP binding or expression of c-jun or c-myc mRNA a...
AbstractLiver regeneration is controlled by a complex network of signaling molecules, and a prominen...
Activation of the immune system in terms of subseptic conditions during liver regeneration is of par...
Liver regeneration is vital for graft survival and adequate organ function. Smad activation regulate...
AbstractIn the present study, we used bone marrow transplanted mice and revealed the role of bone ma...
Studies from Interleukin-6 deficient (IL-6−/−) mice established that IL-6 is essential for normal li...
Studies from Interleukin-6 deficient (IL-6−/−) mice established that IL-6 is essential for normal li...
<div><p>TNF and Fas/FasL are vital components, not only in hepatocyte injury, but are also required ...
The liver is one of the few organs in the body that retains the ability to regenerate following inju...
Recent studies in mice harboring a targeted disruption of genes encoding TNF receptor 1 (TNFR-1) or ...
TNF and Fas/FasL are vital components, not only in hepatocyte injury, but are also required for hepa...
<p>IL-1ra, IL-1β, TNFα and HGF secretion were analyzed by ELISA. IL-6, MCP-1 were measured by a cyto...
Recent studies in mice harboring a targeted disruption of genes encoding TNF receptor 1 (TNFR-1) or ...
Liver regeneration is controlled by a complex network of signaling molecules, and a prominent role f...
<div><p>Bone marrow cells (BMC) migrate to the injured liver after transplantation, contributing to ...
Introduction: Tumor necrosis factor-inducible gene 6 protein (TSG-6), one of the cy...
AbstractLiver regeneration is controlled by a complex network of signaling molecules, and a prominen...
Activation of the immune system in terms of subseptic conditions during liver regeneration is of par...
Liver regeneration is vital for graft survival and adequate organ function. Smad activation regulate...
AbstractIn the present study, we used bone marrow transplanted mice and revealed the role of bone ma...
Studies from Interleukin-6 deficient (IL-6−/−) mice established that IL-6 is essential for normal li...
Studies from Interleukin-6 deficient (IL-6−/−) mice established that IL-6 is essential for normal li...
<div><p>TNF and Fas/FasL are vital components, not only in hepatocyte injury, but are also required ...
The liver is one of the few organs in the body that retains the ability to regenerate following inju...
Recent studies in mice harboring a targeted disruption of genes encoding TNF receptor 1 (TNFR-1) or ...
TNF and Fas/FasL are vital components, not only in hepatocyte injury, but are also required for hepa...
<p>IL-1ra, IL-1β, TNFα and HGF secretion were analyzed by ELISA. IL-6, MCP-1 were measured by a cyto...
Recent studies in mice harboring a targeted disruption of genes encoding TNF receptor 1 (TNFR-1) or ...
Liver regeneration is controlled by a complex network of signaling molecules, and a prominent role f...
<div><p>Bone marrow cells (BMC) migrate to the injured liver after transplantation, contributing to ...
Introduction: Tumor necrosis factor-inducible gene 6 protein (TSG-6), one of the cy...
AbstractLiver regeneration is controlled by a complex network of signaling molecules, and a prominen...
Activation of the immune system in terms of subseptic conditions during liver regeneration is of par...
Liver regeneration is vital for graft survival and adequate organ function. Smad activation regulate...