AbstractSeveral molecules have been identified as receptors or coreceptors for rotavirus infection, including glycans, integrins, and hsc70. In this work we report that the tight junction proteins JAM-A, occludin, and ZO-1 play an important role during rotavirus entry into MA104 cells. JAM-A was found to function as coreceptor for rotavirus strains RRV, Wa, and UK, but not for rotavirus YM. Reassortant viruses derived from rotaviruses RRV and YM showed that the virus spike protein VP4 determines the use of JAM-A as coreceptor
Rotavirus interactions with endogenous cell surface receptors are of fundamental interest in virolog...
AbstractVirus attachment to cells plays an essential role in viral tropism and disease. Reovirus ser...
Rotaviruses are the leading cause of several gastroenteritis in infant and young children worldwide....
Group A rotaviruses are major intestinal pathogens that express potential 41 and 47 integrin ligand ...
International audienceWe found that at the tight junctions (TJs) of Caco-2 cell monolayers, rhesus m...
Integrins 21, X2, and V3 have been implicated in rotavirus cell attachment and entry. The virus spik...
Rotavirus is the single, most important agent of infantile gastroenteritis in many animal species, i...
Rotavirus spike protein VP4 is implicated in several important functions, such as cell attachment, p...
Despite their fundamental role in host defense, many components of epithelial and endothelial tight ...
AbstractRotavirus cell entry is a multistep process, not completely understood, which requires at le...
Tight junctions (TJs) are highly specialized membrane domains involved in many important cellular pr...
Rotavirus spike protein VP4 is implicated in several important functions, such as cell attachment, p...
AbstractRhesus rotavirus (RRV) binds to sialic acid residues on the surface of target cells, and tre...
To initiate infection, non-enveloped viruses must recognize a target cell and penetrate the cell mem...
Introduction: Rotaviruses are the main cause of gastroenteritis in children under five years old. At...
Rotavirus interactions with endogenous cell surface receptors are of fundamental interest in virolog...
AbstractVirus attachment to cells plays an essential role in viral tropism and disease. Reovirus ser...
Rotaviruses are the leading cause of several gastroenteritis in infant and young children worldwide....
Group A rotaviruses are major intestinal pathogens that express potential 41 and 47 integrin ligand ...
International audienceWe found that at the tight junctions (TJs) of Caco-2 cell monolayers, rhesus m...
Integrins 21, X2, and V3 have been implicated in rotavirus cell attachment and entry. The virus spik...
Rotavirus is the single, most important agent of infantile gastroenteritis in many animal species, i...
Rotavirus spike protein VP4 is implicated in several important functions, such as cell attachment, p...
Despite their fundamental role in host defense, many components of epithelial and endothelial tight ...
AbstractRotavirus cell entry is a multistep process, not completely understood, which requires at le...
Tight junctions (TJs) are highly specialized membrane domains involved in many important cellular pr...
Rotavirus spike protein VP4 is implicated in several important functions, such as cell attachment, p...
AbstractRhesus rotavirus (RRV) binds to sialic acid residues on the surface of target cells, and tre...
To initiate infection, non-enveloped viruses must recognize a target cell and penetrate the cell mem...
Introduction: Rotaviruses are the main cause of gastroenteritis in children under five years old. At...
Rotavirus interactions with endogenous cell surface receptors are of fundamental interest in virolog...
AbstractVirus attachment to cells plays an essential role in viral tropism and disease. Reovirus ser...
Rotaviruses are the leading cause of several gastroenteritis in infant and young children worldwide....